PMID- 7458676
OWN - NLM
STAT- MEDLINE
DCOM- 19810317
LR  - 20141120
IS  - 0098-6127 (Print)
IS  - 0098-6127 (Linking)
VI  - 8
IP  - 2
DP  - 1980
TI  - Changes in lipids and lipoproteins in patients with hyperlipidemia type IIb, IV 
      and V treated with different lipid lowering drugs.
PG  - 113-9
AB  - In this study we examined the influence of different lipid lowering drugs 
      (xantinolnicotinate (Xn), bezafibrate (Bf) and a combination of 
      inositolnicotinate and clofibrate (In-Cl)) on the lipid and lipoprotein 
      concentration in 61 hyperlipidemics of the types IIb, IV and V. Treatment with 
      the 3 drugs showed a significant LDL-cholesterol decrease in type IIb and a 
      LDL-cholesterol increase in the types IV and V. Concerning protective HDL 
      lipoproteins an increase of HDL-cholesterol could be observed in all three types 
      only by treatment with xantinolnicotinate and bezafibrate. Concomitantly in type 
      V a type conversion to type IV could be observed under drug treatment regarding 
      the chemical composition of the lipoprotein fractions VLDL, LDL and HDL.
FAU - Hutt, V
AU  - Hutt V
FAU - Wechsler, J G
AU  - Wechsler JG
FAU - Klor, H U
AU  - Klor HU
FAU - Ditschuneit, H
AU  - Ditschuneit H
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Artery
JT  - Artery
JID - 7508494
RN  - 0 (Anticholesteremic Agents)
RN  - 0 (Lipoproteins)
RN  - 0 (Nicotinic Acids)
RN  - 4L6452S749 (Inositol)
RN  - 53PF01Q249 (Clofibric Acid)
RN  - 8G60H12X2D (Xanthinol Niacinate)
RN  - 97C5T2UQ7J (Cholesterol)
RN  - A99MK953KZ (Inositol Niacinate)
RN  - HPN91K7FU3 (Clofibrate)
RN  - Y9449Q51XH (Bezafibrate)
SB  - IM
MH  - Anticholesteremic Agents/*therapeutic use
MH  - Bezafibrate
MH  - Cholesterol/*blood
MH  - Clofibrate/therapeutic use
MH  - Clofibric Acid/analogs & derivatives/therapeutic use
MH  - Humans
MH  - Hyperlipoproteinemia Type II/blood/*drug therapy
MH  - Hyperlipoproteinemia Type IV/blood/*drug therapy
MH  - Hyperlipoproteinemia Type V/blood/*drug therapy
MH  - Inositol/*analogs & derivatives/therapeutic use
MH  - Lipoproteins/*blood
MH  - Nicotinic Acids/*therapeutic use
MH  - Xanthinol Niacinate/therapeutic use
EDAT- 1980/01/01 00:00
MHDA- 1980/01/01 00:01
CRDT- 1980/01/01 00:00
PHST- 1980/01/01 00:00 [pubmed]
PHST- 1980/01/01 00:01 [medline]
PHST- 1980/01/01 00:00 [entrez]
PST - ppublish
SO  - Artery. 1980;8(2):113-9.