PMID- 7472673
OWN - NLM
STAT- MEDLINE
DCOM- 19951212
LR  - 20190830
IS  - 0301-4800 (Print)
IS  - 0301-4800 (Linking)
VI  - 41
IP  - 3
DP  - 1995 Jun
TI  - Effects of fructooligosaccharides on the absorption of iron, calcium and 
      magnesium in iron-deficient anemic rats.
PG  - 281-91
AB  - We investigated the effects of fructooligosaccharides (FO)-feeding on the 
      absorption of iron (Fe), calcium (Ca) and magnesium (Mg) and on the biochemical 
      parameters in Fe-deficient anemic rats. Fe-deficient anemic rats were made by 
      feeding an Fe-deficient diet for 3 weeks. Then these Fe-deficient rats were fed 
      an experimental diet that contained one of two levels of Fe (15 or 30 mg/kg 
      diet), in the form of ferric pyrophosphate, and one of two levels of FO (0 or 50 
      g/kg diet) for 2 weeks. After the rats were fed these experimental diets, 
      FO-feeding increased the hematocrit ratio, the concentration of hemoglobin and 
      the hemoglobin regeneration efficiency during the first week. Also, the apparent 
      absorption of Fe was increased by FO-feeding. The levels of Fe in the diet did 
      not affect the absorption of Ca and Mg. However, FO-feeding increased the 
      absorption of Ca and Mg. FO-feeding lowered the pH and raised the solubility of 
      Fe, Ca and Mg in the cecal contents, suggesting that those increasing effects of 
      FO-feeding on absorption of these minerals is correlated with fermentation of FO 
      in the large intestine, namely, the cecum and colon. We concluded that FO-feeding 
      improved recovery from anemia and increased the absorption of Fe, Ca and Mg in 
      Fe-deficient anemic rats.
FAU - Ohta, A
AU  - Ohta A
AD  - Bioscience Laboratories, Meiji Seika Kaisha, Ltd., Sakado, Japan.
FAU - Ohtsuki, M
AU  - Ohtsuki M
FAU - Baba, S
AU  - Baba S
FAU - Takizawa, T
AU  - Takizawa T
FAU - Adachi, T
AU  - Adachi T
FAU - Kimura, S
AU  - Kimura S
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - J Nutr Sci Vitaminol (Tokyo)
JT  - Journal of nutritional science and vitaminology
JID - 0402640
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Hemoglobins)
RN  - 0 (Oligosaccharides)
RN  - 30237-26-4 (Fructose)
RN  - E1UOL152H7 (Iron)
RN  - I38ZP9992A (Magnesium)
RN  - SY7Q814VUP (Calcium)
SB  - IM
MH  - Absorption
MH  - Anemia, Iron-Deficiency/*diet therapy
MH  - Animals
MH  - Body Weight
MH  - Calcium/*metabolism
MH  - Cecum/metabolism
MH  - Dietary Carbohydrates/administration & dosage/*therapeutic use
MH  - Eating
MH  - Fructose/administration & dosage/*therapeutic use
MH  - Hematocrit
MH  - Hemoglobins/analysis
MH  - Hydrogen-Ion Concentration
MH  - Intestinal Absorption/drug effects
MH  - Iron/administration & dosage/*metabolism
MH  - Magnesium/*metabolism
MH  - Male
MH  - Oligosaccharides/administration & dosage/therapeutic use
MH  - Rats
MH  - Rats, Sprague-Dawley
EDAT- 1995/06/01 00:00
MHDA- 1995/06/01 00:01
CRDT- 1995/06/01 00:00
PHST- 1995/06/01 00:00 [pubmed]
PHST- 1995/06/01 00:01 [medline]
PHST- 1995/06/01 00:00 [entrez]
AID - 10.3177/jnsv.41.281 [doi]
PST - ppublish
SO  - J Nutr Sci Vitaminol (Tokyo). 1995 Jun;41(3):281-91. doi: 10.3177/jnsv.41.281.