PMID- 7472679
OWN - NLM
STAT- MEDLINE
DCOM- 19951212
LR  - 20190830
IS  - 0301-4800 (Print)
IS  - 0301-4800 (Linking)
VI  - 41
IP  - 3
DP  - 1995 Jun
TI  - Selenium levels and glutathione peroxidase activities in blood in an andean 
      high-altitude population.
PG  - 349-61
AB  - Selenium (Se) levels in blood (whole blood, erythrocytes and serum) and blood 
      glutathione peroxidase (GSH-Px) activity were investigated in people living at 
      high altitude in Bolivia (4,000 m above sea level). These parameters were 
      compared to those of people living at low altitude (300 m above sea level). The 
      Se levels in whole blood of the high-altitude subjects did not differ 
      significantly from those of the low-altitude subjects. However, the Se levels in 
      erythrocytes were significantly lower in the high-altitude subjects than in the 
      low-altitude subjects, whereas serum Se levels were higher in the high-altitude 
      subjects than in the low-altitude subjects. GSH-Px activity (Unit/g Hb) was 
      significantly lower in the high-altitude subjects than in the low-altitude 
      subjects. The mean corpuscular Hb concentration (MCHC), an indicator of the age 
      of erythrocytes, in the high-altitude subjects was significantly higher than in 
      the low-altitude subjects. These results show that the GSH-Px activity in the 
      blood of the high-altitude subjects is relatively low. This may be due to their 
      aged erythrocytes and/or to relatively low Se intake in the high-altitude 
      population compared with low-altitude population.
FAU - Imai, H
AU  - Imai H
AD  - Regional Environment Division, National Institute for Environmental Studies, 
      Tsukuba, Japan.
FAU - Kashiwazaki, H
AU  - Kashiwazaki H
FAU - Suzuki, T
AU  - Suzuki T
FAU - Kabuto, M
AU  - Kabuto M
FAU - Himeno, S
AU  - Himeno S
FAU - Watanabe, C
AU  - Watanabe C
FAU - Moji, K
AU  - Moji K
FAU - Kim, S W
AU  - Kim SW
FAU - Rivera, J O
AU  - Rivera JO
FAU - Takemoto, T
AU  - Takemoto T
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - J Nutr Sci Vitaminol (Tokyo)
JT  - Journal of nutritional science and vitaminology
JID - 0402640
RN  - 0 (Hemoglobins)
RN  - EC 1.11.1.9 (Glutathione Peroxidase)
RN  - H6241UJ22B (Selenium)
SB  - IM
EIN - J Nutr Sci Vitaminol (Tokyo) 1995 Oct;41(5):followi
MH  - Adolescent
MH  - Adult
MH  - *Altitude
MH  - Bolivia
MH  - Child
MH  - Child, Preschool
MH  - Erythrocyte Indices
MH  - Erythrocytes/metabolism
MH  - Female
MH  - Glutathione Peroxidase/*blood
MH  - Hematocrit
MH  - Hemoglobins/metabolism
MH  - Humans
MH  - Infant
MH  - Male
MH  - Reference Values
MH  - Selenium/*blood
EDAT- 1995/06/01 00:00
MHDA- 1995/06/01 00:01
CRDT- 1995/06/01 00:00
PHST- 1995/06/01 00:00 [pubmed]
PHST- 1995/06/01 00:01 [medline]
PHST- 1995/06/01 00:00 [entrez]
AID - 10.3177/jnsv.41.349 [doi]
PST - ppublish
SO  - J Nutr Sci Vitaminol (Tokyo). 1995 Jun;41(3):349-61. doi: 10.3177/jnsv.41.349.