PMID- 7483293
OWN - NLM
STAT- MEDLINE
DCOM- 19951212
LR  - 20191023
IS  - 0920-8569 (Print)
IS  - 0920-8569 (Linking)
VI  - 10
IP  - 1
DP  - 1995
TI  - HTLV-I from Iranian Mashhadi Jews in Israel is phylogenetically related to that 
      of Japan, India, and South America rather than to that of Africa and Melanesia.
PG  - 85-90
AB  - A new endemic focus of human T-lymphotropic virus type I (HTLV-I) was recently 
      reported among Mashhadi Jews, a group of immigrants from northeastern Iran to 
      Israel. We extracted DNAs from fresh peripheral blood mononuclear cells (PBMCs) 
      and/or gargle mouthwash from 10 HTLV-I carriers, who consisted of members of one 
      family, and HTLV-I-associated myelopathy (HAM) and adult T-cell leukemia (ATL) 
      patients. Long terminal repeat (LTR) regions of proviral DNAs were sequenced and 
      analyzed phylogenetically. In a phylogenetic tree, all the Mashhadi HTLV-I 
      isolates belonged to subtype A, one of the three subtypes of the cosmopolitan 
      type of HTLV-I, and made a tight cluster distinct from the other isolates of 
      subtype A from Japan, India, the Caribbean Basin, and South America. Although a 
      few nucleotide substitutions were observed among the clones sequenced, no 
      characteristic sequence variation was found in different disease manifestations, 
      even in one family or different sources of DNA preparation.
FAU - Yamashita, M
AU  - Yamashita M
AD  - Laboratory of Pathogenic Virus, Kyoto University, Japan.
FAU - Achiron, A
AU  - Achiron A
FAU - Miura, T
AU  - Miura T
FAU - Takehisa, J
AU  - Takehisa J
FAU - Ido, E
AU  - Ido E
FAU - Igarashi, T
AU  - Igarashi T
FAU - Ibuki, K
AU  - Ibuki K
FAU - Osame, M
AU  - Osame M
FAU - Sonoda, S
AU  - Sonoda S
FAU - Melamed, E
AU  - Melamed E
AU  - et al.
LA  - eng
SI  - GENBANK/D38382
SI  - GENBANK/D38383
SI  - GENBANK/D38384
SI  - GENBANK/D38385
SI  - GENBANK/D38386
SI  - GENBANK/D38387
SI  - GENBANK/D38388
SI  - GENBANK/D38389
SI  - GENBANK/D38390
SI  - GENBANK/D38391
SI  - GENBANK/D38392
SI  - GENBANK/D38393
SI  - GENBANK/D38394
SI  - GENBANK/D38395
SI  - GENBANK/D38396
SI  - GENBANK/D38397
SI  - GENBANK/D38398
SI  - GENBANK/D38399
SI  - GENBANK/D38400
SI  - GENBANK/D38401
SI  - GENBANK/D38402
SI  - GENBANK/D38403
PT  - Journal Article
PL  - United States
TA  - Virus Genes
JT  - Virus genes
JID - 8803967
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Adult
MH  - Africa
MH  - Aged
MH  - Base Sequence
MH  - Carrier State
MH  - DNA, Viral
MH  - Female
MH  - HTLV-I Infections/blood/*virology
MH  - Human T-lymphotropic virus 1/*classification/isolation & purification
MH  - Humans
MH  - India
MH  - Iran
MH  - Israel
MH  - Japan
MH  - Jews
MH  - Leukemia, T-Cell/blood/virology
MH  - Leukocytes, Mononuclear/virology
MH  - Male
MH  - Melanesia
MH  - Middle Aged
MH  - Molecular Sequence Data
MH  - Paraparesis, Tropical Spastic/blood/virology
MH  - Phylogeny
MH  - South America
EDAT- 1995/01/01 00:00
MHDA- 1995/01/01 00:01
CRDT- 1995/01/01 00:00
PHST- 1995/01/01 00:00 [pubmed]
PHST- 1995/01/01 00:01 [medline]
PHST- 1995/01/01 00:00 [entrez]
AID - 10.1007/BF01724300 [doi]
PST - ppublish
SO  - Virus Genes. 1995;10(1):85-90. doi: 10.1007/BF01724300.