PMID- 7483822 OWN - NLM STAT- MEDLINE DCOM- 19951212 LR - 20190909 IS - 0168-1702 (Print) IS - 0168-1702 (Linking) VI - 37 IP - 1 DP - 1995 Jun TI - Identification of the major capsid protein gene of human herpesvirus 7. PG - 55-62 AB - Two human herpesvirus 6 (HHV-6) open reading frames were identified with significant amino acid similarity to UL86 (major capsid protein, MCP) and UL85 of human cytomegalovirus (HCMV) in human herpesvirus 7 (HHV-7) genes. The predicted lengths of the complete HHV-7 MCP and the HCMV-UL85 open reading frames were 1344 and 293 amino acids with estimated molecular weights of approximately 153 and 33 kDa, respectively. Computer analysis showed that the amino acid of HHV-7 MCP was 61% identical to the MCP of HHV-6 variants A and B, 28% to HCMV. These results suggest that HHV-7 is more closely related to HHV-6 than to HCMV. FAU - Mukai, T AU - Mukai T AD - Department of Virology, Osaka University, Japan. FAU - Isegawa, Y AU - Isegawa Y FAU - Yamanishi, K AU - Yamanishi K LA - eng SI - GENBANK/D32005 PT - Journal Article PL - Netherlands TA - Virus Res JT - Virus research JID - 8410979 RN - 0 (DNA Primers) SB - IM MH - Adult MH - Animals MH - Base Sequence MH - Capsid/*genetics MH - Cells, Cultured MH - Cytomegalovirus/classification/genetics MH - DNA Primers MH - Herpesviridae/genetics/metabolism MH - Herpesvirus 6, Human/classification/genetics MH - Herpesvirus 7, Human/classification/*genetics/isolation & purification MH - Humans MH - Molecular Sequence Data MH - Open Reading Frames MH - Phylogeny MH - Sequence Homology, Nucleic Acid EDAT- 1995/06/01 00:00 MHDA- 1995/06/01 00:01 CRDT- 1995/06/01 00:00 PHST- 1995/06/01 00:00 [pubmed] PHST- 1995/06/01 00:01 [medline] PHST- 1995/06/01 00:00 [entrez] AID - 016817029500022I [pii] AID - 10.1016/0168-1702(95)00022-i [doi] PST - ppublish SO - Virus Res. 1995 Jun;37(1):55-62. doi: 10.1016/0168-1702(95)00022-i.