PMID- 750274
OWN - NLM
STAT- MEDLINE
DCOM- 19790728
LR  - 20141003
IS  - 0016-450X (Print)
IS  - 0016-450X (Linking)
VI  - 69
IP  - 6
DP  - 1978 Dec
TI  - Effect of BCG cell-wall skeleton immunotherapy on the peripheral blood 
      lymphocytes in patients with lung cancer after radiotherapy.
PG  - 819-24
AB  - The effect of radiotherapy on peripheral blood lymphocytes (PBL) of lung cancer 
      and the effect of BCG cell-wall skeleton (BCG-CWS) on recovery of impaired PBL 
      were examined. A remarkable depression of the absolute number of E- or 
      EAC-rosette cells and of the response of PBL to mitogens were observed 
      immediately after radiotherapy, and these continued for several months. With 
      BCG-CWS immunotherapy, the response of PBL to phytohemagglutinin recovered 
      rapidly, compared with non-vaccinated patients. The response of PBL to pokeweed 
      mitogen seemed to give similar results. These results suggested that BCG-CWS 
      injection to the patient receiving radiotherapy was effective for recovery of 
      T-cell response.
FAU - Nishikawa, H
AU  - Nishikawa H
FAU - Yasaki, S
AU  - Yasaki S
FAU - Yoshimoto, T
AU  - Yoshimoto T
FAU - Sakatani, M
AU  - Sakatani M
FAU - Itoh, M
AU  - Itoh M
FAU - Masuno, T
AU  - Masuno T
FAU - Namba, M
AU  - Namba M
FAU - Ogura, T
AU  - Ogura T
FAU - Hirao, F
AU  - Hirao F
FAU - Azuma, I
AU  - Azuma I
FAU - Yamamura, Y
AU  - Yamamura Y
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Gan
JT  - Gan
JID - 0151745
RN  - 0 (BCG Vaccine)
RN  - 0 (Mitogens)
SB  - IM
MH  - Adenocarcinoma/*therapy
MH  - BCG Vaccine/*therapeutic use
MH  - Carcinoma, Squamous Cell/*therapy
MH  - Cell Wall/immunology
MH  - Female
MH  - Humans
MH  - *Immunotherapy
MH  - Lung Neoplasms/immunology/radiotherapy/*therapy
MH  - Lymphocyte Activation/radiation effects
MH  - Male
MH  - Middle Aged
MH  - Mitogens/pharmacology
MH  - Radiotherapy/adverse effects
MH  - Rosette Formation
EDAT- 1978/12/01 00:00
MHDA- 1978/12/01 00:01
CRDT- 1978/12/01 00:00
PHST- 1978/12/01 00:00 [pubmed]
PHST- 1978/12/01 00:01 [medline]
PHST- 1978/12/01 00:00 [entrez]
PST - ppublish
SO  - Gan. 1978 Dec;69(6):819-24.