PMID- 7512365
OWN - NLM
STAT- MEDLINE
DCOM- 19940513
LR  - 20191023
IS  - 1045-2257 (Print)
IS  - 1045-2257 (Linking)
VI  - 8
IP  - 4
DP  - 1993 Dec
TI  - Molecular mapping of the chromosome 11 breakpoint of t(11;17)(q13;q21) in a 
      t(11;14)(q13;q32)-positive B non-Hodgkin's lymphoma.
PG  - 224-9
AB  - The FAU gene is the cellular homologue of the viral FOX sequences in the genome 
      of the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV); the viral FOX 
      sequences have been shown to increase the transforming capacity of FBR-MuSV in 
      vitro. The human FAU gene has recently been isolated, characterized, and mapped 
      to chromosome band 11q13. Here, we report results of fluorescence in situ 
      hybridization (FISH) analysis which indicate that the FAU gene maps proximally to 
      the putative oncogene BCL1 at 11q13. Furthermore, we identified a 
      t(11;17)(q13;q21) translocation in tumor cells of a t(11;14)(q13;q32)-positive 
      B-cell non-Hodgkin's lymphoma patient by FISH analysis using a FAU containing 
      cosmid clone as molecular probe and by double-colour chromosome painting analysis 
      using chromosome 11- and chromosome 17-specific painting probes. The position of 
      the chromosome 11 breakpoint of the t(11;17) translocation was pinpointed to a 
      human DNA region around the FAU gene of about 40 kbp.
FAU - Wlodarska, I
AU  - Wlodarska I
AD  - Center for Human Genetics, University of Leuven, Belgium.
FAU - Schoenmakers, E
AU  - Schoenmakers E
FAU - Kas, K
AU  - Kas K
FAU - Merregaert, J
AU  - Merregaert J
FAU - Lemahieu, V
AU  - Lemahieu V
FAU - Weier, U
AU  - Weier U
FAU - Van den Berghe, H
AU  - Van den Berghe H
FAU - Van de Ven, W J
AU  - Van de Ven WJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Genes Chromosomes Cancer
JT  - Genes, chromosomes & cancer
JID - 9007329
RN  - 0 (DNA Probes)
RN  - 0 (Ribosomal Proteins)
RN  - 148266-62-0 (FAU protein, human)
SB  - IM
GS  - BCL1
GS  - FAU
GS  - FOX
GS  - MYC
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 11/*ultrastructure
MH  - Chromosomes, Human, Pair 14/*ultrastructure
MH  - Chromosomes, Human, Pair 17/*ultrastructure
MH  - DNA Probes
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics
MH  - Lymphoma, Follicular/*genetics
MH  - Male
MH  - *Oncogenes
MH  - Ribosomal Proteins/*genetics
MH  - *Translocation, Genetic
EDAT- 1993/12/01 00:00
MHDA- 1993/12/01 00:01
CRDT- 1993/12/01 00:00
PHST- 1993/12/01 00:00 [pubmed]
PHST- 1993/12/01 00:01 [medline]
PHST- 1993/12/01 00:00 [entrez]
AID - 10.1002/gcc.2870080404 [doi]
PST - ppublish
SO  - Genes Chromosomes Cancer. 1993 Dec;8(4):224-9. doi: 10.1002/gcc.2870080404.