PMID- 7520263
OWN - NLM
STAT- MEDLINE
DCOM- 19940920
LR  - 20191023
IS  - 1045-2257 (Print)
IS  - 1045-2257 (Linking)
VI  - 10
IP  - 2
DP  - 1994 Jun
TI  - 1;17 translocations and other chromosome 17 rearrangements in human primary 
      neuroblastoma tumors and cell lines.
PG  - 103-14
AB  - We report on the finding of a t(1;17) in two primary neuroblastomas. Subsequent 
      fluorescence in situ hybridization (FISH) analysis revealed the presence of 1;17 
      translocations in four out of nine neuroblastoma cell lines. The chromosome 1 
      short arm breakpoints were determined using region-specific probes. FISH 
      screening also demonstrated or confirmed the presence of 11;17 translocations in 
      three cell lines and other chromosome 17 rearrangements in those cell lines that 
      did not carry a t(1;17) or t(11;17). Our data extend previous cytogenetic 
      findings and suggest that, in addition to the known involvement of chromosome 1, 
      one or more genes on chromosome 17 also play a role in neuroblastoma development.
FAU - Van Roy, N
AU  - Van Roy N
AD  - Department of Medical Genetics, University Hospital, Gent, Belgium.
FAU - Laureys, G
AU  - Laureys G
FAU - Cheng, N C
AU  - Cheng NC
FAU - Willem, P
AU  - Willem P
FAU - Opdenakker, G
AU  - Opdenakker G
FAU - Versteeg, R
AU  - Versteeg R
FAU - Speleman, F
AU  - Speleman F
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Genes Chromosomes Cancer
JT  - Genes, chromosomes & cancer
JID - 9007329
SB  - IM
MH  - Adrenal Gland Neoplasms/genetics/pathology/secondary
MH  - Bone Marrow/pathology
MH  - Bone Neoplasms/genetics/pathology/secondary
MH  - Brain Neoplasms/*genetics/pathology
MH  - Cell Line
MH  - Child, Preschool
MH  - *Chromosome Aberrations
MH  - Chromosome Banding
MH  - *Chromosome Disorders
MH  - *Chromosomes, Human, Pair 1
MH  - *Chromosomes, Human, Pair 17
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Male
MH  - Neuroblastoma/*genetics/pathology/secondary
MH  - *Translocation, Genetic
MH  - Tumor Cells, Cultured
EDAT- 1994/06/01 00:00
MHDA- 1994/06/01 00:01
CRDT- 1994/06/01 00:00
PHST- 1994/06/01 00:00 [pubmed]
PHST- 1994/06/01 00:01 [medline]
PHST- 1994/06/01 00:00 [entrez]
AID - 10.1002/gcc.2870100205 [doi]
PST - ppublish
SO  - Genes Chromosomes Cancer. 1994 Jun;10(2):103-14. doi: 10.1002/gcc.2870100205.