PMID- 7525414
OWN - NLM
STAT- MEDLINE
DCOM- 19941227
LR  - 20190707
IS  - 0378-1119 (Print)
IS  - 0378-1119 (Linking)
VI  - 149
IP  - 2
DP  - 1994 Nov 18
TI  - Tas, a retrotransposon from the parasitic nematode Ascaris lumbricoides.
PG  - 219-25
AB  - The cloned retrotransposon Tas OE3 from the genome of the parasitic nematode 
      Ascaris lumbricoides was completely sequenced. The element is flanked by long 
      terminal repeats (LTR) and contains three distinct regions encoding putative 
      proteins typical for retroid elements. The first region, ORF1, encodes a putative 
      Gag protein including a 'Leu zipper', a nucleic acid binding motif, as well as an 
      aspartic protease domain. The second region contains an incomplete ORF (ORF2) 
      with sequence similarities to known retroviral reverse transcriptases (RT), 
      ribonucleases H and integrases. A third ORF, which is located adjacent to the 3' 
      LTR, might encode an env-like protein. Based on amino-acid sequence analysis of 
      the RT domain, Tas falls into a new subgroup of LTR-containing retrotransposons.
FAU - Felder, H
AU  - Felder H
AD  - Institute of Zoology, University of Fribourg, Switzerland.
FAU - Herzceg, A
AU  - Herzceg A
FAU - de Chastonay, Y
AU  - de Chastonay Y
FAU - Aeby, P
AU  - Aeby P
FAU - Tobler, H
AU  - Tobler H
FAU - Muller, F
AU  - Muller F
LA  - eng
SI  - GENBANK/Z29712
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Gene
JT  - Gene
JID - 7706761
RN  - 0 (DNA Primers)
RN  - 0 (Gene Products, env)
RN  - 0 (Gene Products, gag)
RN  - 0 (Retroelements)
RN  - 0 (Viral Proteins)
RN  - EC 2.7.7.- (DNA Nucleotidyltransferases)
RN  - EC 2.7.7.- (Integrases)
RN  - EC 2.7.7.49 (RNA-Directed DNA Polymerase)
RN  - EC 3.1.26.4 (Ribonuclease H)
RN  - EC 3.4.23.- (Aspartic Acid Endopeptidases)
SB  - IM
GS  - Tas
MH  - Amino Acid Sequence
MH  - Animals
MH  - Ascaris lumbricoides/*genetics
MH  - Aspartic Acid Endopeptidases/biosynthesis/genetics
MH  - Base Sequence
MH  - Cloning, Molecular
MH  - DNA Nucleotidyltransferases/biosynthesis/genetics
MH  - DNA Primers
MH  - Gene Products, env/biosynthesis/genetics
MH  - Gene Products, gag/biosynthesis/genetics
MH  - Integrases
MH  - Leucine Zippers
MH  - Molecular Sequence Data
MH  - Open Reading Frames
MH  - RNA-Directed DNA Polymerase/biosynthesis/genetics
MH  - Repetitive Sequences, Nucleic Acid
MH  - *Retroelements
MH  - Ribonuclease H/biosynthesis/genetics
MH  - Sequence Homology, Amino Acid
MH  - Viral Proteins/biosynthesis/*genetics
EDAT- 1994/11/18 00:00
MHDA- 1994/11/18 00:01
CRDT- 1994/11/18 00:00
PHST- 1994/11/18 00:00 [pubmed]
PHST- 1994/11/18 00:01 [medline]
PHST- 1994/11/18 00:00 [entrez]
AID - 0378-1119(94)90153-8 [pii]
AID - 10.1016/0378-1119(94)90153-8 [doi]
PST - ppublish
SO  - Gene. 1994 Nov 18;149(2):219-25. doi: 10.1016/0378-1119(94)90153-8.