PMID- 7527906 OWN - NLM STAT- MEDLINE DCOM- 19950118 LR - 20190702 IS - 0027-5107 (Print) IS - 0027-5107 (Linking) VI - 325 IP - 4 DP - 1994 Dec TI - The LacZ transgene in MutaMouse maps to chromosome 3. PG - 145-8 AB - Transgenic mouse models are being used with increasing frequency for mutational and toxicological studies. One such system. MutaMouse, contains a stably integrated lambda-gt10LacZ shuttle vector in the mouse genome. We describe the use of dual color fluorescence in situ hybridization (FISH) with Mus musculus whole chromosome paints and lambda DNA to map the integration site of the lambda transgene to band C on mouse chromosome 3. FAU - Swiger, R R AU - Swiger RR AD - Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, CA 94551. FAU - Myhr, B AU - Myhr B FAU - Tucker, J D AU - Tucker JD LA - eng PT - Journal Article PL - Netherlands TA - Mutat Res JT - Mutation research JID - 0400763 SB - IM MH - Animals MH - *Chromosome Mapping MH - Female MH - In Situ Hybridization, Fluorescence MH - Lac Operon/*genetics MH - Mice MH - Mice, Transgenic/*genetics EDAT- 1994/12/01 00:00 MHDA- 1994/12/01 00:01 CRDT- 1994/12/01 00:00 PHST- 1994/12/01 00:00 [pubmed] PHST- 1994/12/01 00:01 [medline] PHST- 1994/12/01 00:00 [entrez] AID - 0165-7992(94)90077-9 [pii] AID - 10.1016/0165-7992(94)90077-9 [doi] PST - ppublish SO - Mutat Res. 1994 Dec;325(4):145-8. doi: 10.1016/0165-7992(94)90077-9.