PMID- 7531042
OWN - NLM
STAT- MEDLINE
DCOM- 19950309
LR  - 20191031
IS  - 0803-5326 (Print)
IS  - 0803-5326 (Linking)
VI  - 404
DP  - 1994 Nov
TI  - Development after prenatal exposure to cocaine, heroin and methadone.
PG  - 40-6
AB  - In Amsterdam a longitudinal, prospective and multidisciplinary study on the 
      development of infants of drug-dependent mothers (IDDM) was started in 1983: 35 
      IDDM and 35 reference infants were originally enrolled. The drug-dependent women 
      had used combinations of methadone, heroin, cocaine and other drugs during 
      pregnancy. Of the IDDM, 80% had to be treated pharmaceutically for neonatal 
      abstinence symptoms (NAS). Physical, neurological, cognitive and the 
      socio-emotional development of the children were studied regularly from birth 
      until 5.5 years of age. Differences between the reference group and the IDDM were 
      found most clearly in cognitive development. The IDDM also had more behavioural 
      problems at some of the ages studied. No group differences were seen in motor 
      development. So far the results of the study show that IDDM and their caregivers 
      need extra support in order to improve early communication and the children's 
      cognitive development.
FAU - van Baar, A L
AU  - van Baar AL
AD  - Department of Neonataology, Academical Medical Center, Amsterdam, The 
      Netherlands.
FAU - Soepatmi, S
AU  - Soepatmi S
FAU - Gunning, W B
AU  - Gunning WB
FAU - Akkerhuis, G W
AU  - Akkerhuis GW
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Norway
TA  - Acta Paediatr Suppl
JT  - Acta paediatrica (Oslo, Norway : 1992). Supplement
JID - 9315043
RN  - I5Y540LHVR (Cocaine)
RN  - UC6VBE7V1Z (Methadone)
SB  - IM
MH  - Case-Control Studies
MH  - Child
MH  - Child of Impaired Parents
MH  - Child, Preschool
MH  - *Cocaine
MH  - *Developmental Disabilities/chemically induced/physiopathology/psychology
MH  - Female
MH  - Heroin Dependence/*complications
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - *Methadone
MH  - Neonatal Abstinence Syndrome
MH  - Pregnancy
MH  - *Pregnancy Complications
MH  - Prospective Studies
MH  - Risk Factors
MH  - Substance-Related Disorders/*complications
EDAT- 1994/11/01 00:00
MHDA- 1994/11/01 00:01
CRDT- 1994/11/01 00:00
PHST- 1994/11/01 00:00 [pubmed]
PHST- 1994/11/01 00:01 [medline]
PHST- 1994/11/01 00:00 [entrez]
AID - 10.1111/j.1651-2227.1994.tb13383.x [doi]
PST - ppublish
SO  - Acta Paediatr Suppl. 1994 Nov;404:40-6. doi: 10.1111/j.1651-2227.1994.tb13383.x.