PMID- 7558120
OWN - NLM
STAT- MEDLINE
DCOM- 19951106
LR  - 20181113
IS  - 0019-2805 (Print)
IS  - 1365-2567 (Electronic)
IS  - 0019-2805 (Linking)
VI  - 85
IP  - 3
DP  - 1995 Jul
TI  - The induction of respiratory syncytial virus-specific cytotoxic T-cell responses 
      following immunization with a synthetic peptide containing a fusion peptide 
      linked to a cytotoxic T lymphocyte epitope.
PG  - 347-50
AB  - Previously published work has shown that a cytotoxic T-cell epitope (CTL) 
      representing residues 82-90 of the M2 protein of respiratory syncytial virus 
      (RSV) is the target for a protective response against the virus. In this report, 
      we demonstrate that a synthetic peptide representing residues 81-95, when 
      covalently linked to a fusion peptide derived from the conserved N-terminal 19 
      residues of the F1 protein of measles virus efficiently primes RSV-specific CTLs 
      in vivo following immunization without adjuvant.
FAU - Hsu, S C
AU  - Hsu SC
AD  - Department of Clinical Sciences, London School of Hygiene & Tropical Medicine, 
      UK.
FAU - Shaw, D M
AU  - Shaw DM
FAU - Steward, M W
AU  - Steward MW
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Immunology
JT  - Immunology
JID - 0374672
RN  - 0 (Antigens, Viral)
RN  - 0 (Peptide Fragments)
RN  - 0 (Viral Fusion Proteins)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Antigens, Viral/*immunology
MH  - Cytotoxicity, Immunologic
MH  - *Immunization
MH  - Mice
MH  - Mice, Inbred BALB C
MH  - Mice, Inbred Strains
MH  - Molecular Sequence Data
MH  - Peptide Fragments/*immunology
MH  - Respiratory Syncytial Virus, Human/*immunology
MH  - T-Lymphocytes, Cytotoxic/*immunology
MH  - Viral Fusion Proteins/immunology
PMC - PMC1383905
EDAT- 1995/07/01 00:00
MHDA- 1995/07/01 00:01
PMCR- 1996/07/01
CRDT- 1995/07/01 00:00
PHST- 1995/07/01 00:00 [pubmed]
PHST- 1995/07/01 00:01 [medline]
PHST- 1995/07/01 00:00 [entrez]
PHST- 1996/07/01 00:00 [pmc-release]
PST - ppublish
SO  - Immunology. 1995 Jul;85(3):347-50.