PMID- 7579322
OWN - NLM
STAT- MEDLINE
DCOM- 19951201
LR  - 20191031
IS  - 0962-8479 (Print)
IS  - 0962-8479 (Linking)
VI  - 76
IP  - 4
DP  - 1995 Aug
TI  - Tumor necrosis factor-alpha (TNF-alpha) in pleural fluids.
PG  - 370-1
AB  - Our study was undertaken to investigate the role of tumor necrosis factor-alpha 
      (TNF-alpha) at the site of disease activity in tuberculous pleuritis (TP). 
      Concentrations of TNF-alpha were measured directly by radioimmunoassay (RIA) in 
      the pleural fluid (PF) and plasma (P) of patients with TP (n = 14), malignant 
      effusions (n = 18) and transudates (n = 7). Among these three groups mean plasma 
      levels of TNF-alpha were not statistically significant (P > 0.05), but in the TP 
      group mean levels of TNF-alpha in PF were significantly higher than in the cancer 
      and transudate groups (P < 0.001), and there was no significant difference 
      between the cancer and transudate groups (P > 0.05). These results may indicate a 
      local synthesis of TNF-alpha by cells within the pleural cavity in this disease.
FAU - Gursel, G
AU  - Gursel G
AD  - Department of Chest Diseases, Gazi University School of Medicine, Turkey.
FAU - Gokcora, N
AU  - Gokcora N
FAU - Elbeg, S
AU  - Elbeg S
FAU - Samurkasoglu, B
AU  - Samurkasoglu B
FAU - Ekim, N
AU  - Ekim N
LA  - eng
PT  - Journal Article
PL  - Scotland
TA  - Tuber Lung Dis
JT  - Tubercle and lung disease : the official journal of the International Union 
      against Tuberculosis and Lung Disease
JID - 9212467
RN  - 0 (Biomarkers)
RN  - 0 (Tumor Necrosis Factor-alpha)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Biomarkers/analysis
MH  - Exudates and Transudates/chemistry
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pleural Effusion/*metabolism
MH  - Pleural Effusion, Malignant/chemistry
MH  - Tuberculosis, Pleural/*metabolism
MH  - Tumor Necrosis Factor-alpha/*analysis
EDAT- 1995/08/01 00:00
MHDA- 1995/08/01 00:01
CRDT- 1995/08/01 00:00
PHST- 1995/08/01 00:00 [pubmed]
PHST- 1995/08/01 00:01 [medline]
PHST- 1995/08/01 00:00 [entrez]
AID - 10.1016/s0962-8479(05)80039-5 [doi]
PST - ppublish
SO  - Tuber Lung Dis. 1995 Aug;76(4):370-1. doi: 10.1016/s0962-8479(05)80039-5.