PMID- 7586391
OWN - NLM
STAT- MEDLINE
DCOM- 19951228
LR  - 20190623
IS  - 0009-7322 (Print)
IS  - 0009-7322 (Linking)
VI  - 92
IP  - 9 Suppl
DP  - 1995 Nov 1
TI  - Influence of coronary artery bypass and age on clinical performance after aortic 
      and mitral valve replacement with biological and mechanical prostheses.
PG  - II101-6
AB  - The influence of prosthetic type, age, and coronary artery bypass grafting (CABG) 
      on valve-related complications by valve position was evaluated in a population of 
      2353 bioprosthesis patients (mean age, 66.5 years; range, 13 to 89 years) and in 
      a population of 1112 mechanical prosthesis patients (mean age, 59.1 years; range, 
      13 to 91 years). The follow-up was complete to 96% and 98%, respectively, for the 
      bioprosthesis and mechanical prosthesis groups. The patient groups were evaluated 
      by actuarial assessment of survival and valve complications and composites. 
      Preoperative factors were evaluated for determination of significant independent 
      predictors by multivariate proportional-hazard regression analysis. CABG was an 
      influential factor in the actuarial analysis. Survival was superior for aortic 
      mechanical replacements without CABG and for mitral replacements, both biological 
      and mechanical, without CABG (P < .05). The freedom from thromboembolism (TE) and 
      antithromboembolic hemorrhage (ATH) was greater for biological prostheses with 
      and without CABG for aortic replacements (P < .05) but not for mitral 
      replacements (P = NS). The freedom from valve-related mortality was not 
      influenced by CABG for either position (P = NS). The freedom from valve-related 
      reoperation was greater for biological prostheses with CABG than without CABG for 
      both aortic and mitral replacements (P < .05). The evaluation of covariates as 
      independent predictors revealed CABG to be a nonpredictor for aortic valve 
      replacement (AVR) (P = NS) but a predictor of survival and valve-related 
      reoperation for mitral valve replacement (MVR) (P < .05).(ABSTRACT TRUNCATED AT 
      250 WORDS)
FAU - Jamieson, W R
AU  - Jamieson WR
AD  - St Paul's Hospital, Vancouver, BC, Canada.
FAU - Munro, A I
AU  - Munro AI
FAU - Burr, L H
AU  - Burr LH
FAU - Germann, E
AU  - Germann E
FAU - Miyagishima, R T
AU  - Miyagishima RT
FAU - Ling, H
AU  - Ling H
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Circulation
JT  - Circulation
JID - 0147763
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Animals
MH  - Aortic Valve/surgery
MH  - *Bioprosthesis
MH  - *Coronary Artery Bypass
MH  - Follow-Up Studies
MH  - *Heart Valve Prosthesis
MH  - Humans
MH  - Middle Aged
MH  - Mitral Valve/surgery
MH  - Proportional Hazards Models
MH  - Risk Factors
MH  - Survival Analysis
MH  - Swine
MH  - Treatment Outcome
EDAT- 1995/11/01 00:00
MHDA- 1995/11/01 00:01
CRDT- 1995/11/01 00:00
PHST- 1995/11/01 00:00 [pubmed]
PHST- 1995/11/01 00:01 [medline]
PHST- 1995/11/01 00:00 [entrez]
AID - 10.1161/01.cir.92.9.101 [doi]
PST - ppublish
SO  - Circulation. 1995 Nov 1;92(9 Suppl):II101-6. doi: 10.1161/01.cir.92.9.101.