PMID- 7587389
OWN - NLM
STAT- MEDLINE
DCOM- 19951124
LR  - 20180214
IS  - 0301-0171 (Print)
IS  - 0301-0171 (Linking)
VI  - 71
IP  - 3
DP  - 1995
TI  - Assignment of the mouse homologue of a human MEN1 candidate gene, phospholipase 
      C-beta 3 (Plcb3), to chromosome region 19B by FISH.
PG  - 257-9
AB  - A recent study using comparative mapping analysis suggests that the proximal 
      segment of mouse chromosome 19 contains the mouse homologs of the human multiple 
      endocrine neoplasia type 1 (MEN1) flanking markers proximal to the locus. We have 
      recently shown that phospholipase C-beta 3 (PLCB3) is a candidate gene for the 
      MEN1 syndrome. In the present investigation we used fluorescence in situ 
      hybridization with a genomic DNA clone for mouse Plcb3, and mapped the locus to 
      chromosome region 19B. This is in agreement with the comparative mapping of the 
      MEN1 flanking markers in mouse.
FAU - Gobl, A E
AU  - Gobl AE
AD  - Department of Internal Medicine, University Hospital, Uppsala, Sweden.
FAU - Chowdhary, B P
AU  - Chowdhary BP
FAU - Shu, W
AU  - Shu W
FAU - Eriksson, L
AU  - Eriksson L
FAU - Larsson, C
AU  - Larsson C
FAU - Weber, G
AU  - Weber G
FAU - Oberg, K
AU  - Oberg K
FAU - Skogseid, B
AU  - Skogseid B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Switzerland
TA  - Cytogenet Cell Genet
JT  - Cytogenetics and cell genetics
JID - 0367735
RN  - 0 (Isoenzymes)
RN  - EC 3.1.4.- (Type C Phospholipases)
RN  - EC 3.1.4.11 (PLCB3 protein, human)
RN  - EC 3.1.4.11 (Phospholipase C beta)
RN  - EC 3.1.4.11 (Plcb3 protein, mouse)
SB  - IM
MH  - Animals
MH  - *Chromosome Mapping
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Isoenzymes/*genetics
MH  - Mice
MH  - Multiple Endocrine Neoplasia Type 1/*genetics
MH  - Phospholipase C beta
MH  - Type C Phospholipases/*genetics
EDAT- 1995/01/01 00:00
MHDA- 1995/01/01 00:01
CRDT- 1995/01/01 00:00
PHST- 1995/01/01 00:00 [pubmed]
PHST- 1995/01/01 00:01 [medline]
PHST- 1995/01/01 00:00 [entrez]
AID - 10.1159/000134122 [doi]
PST - ppublish
SO  - Cytogenet Cell Genet. 1995;71(3):257-9. doi: 10.1159/000134122.