PMID- 7595175 OWN - NLM STAT- MEDLINE DCOM- 19951213 LR - 20190904 IS - 0954-6820 (Print) IS - 0954-6820 (Linking) VI - 238 IP - 4 DP - 1995 Oct TI - Dramatic responses to intravenous immunoglobulin in vasculitis. PG - 375-7 AB - Intravenous immunoglobulin (IVIG) has been successfully used to treat autoimmune diseases. We report dramatic, rapid and sustained responses to its use in two cases of vasculitis: a patient with primary angitis of the central nervous system: and a patient with hepatitis-B-antigen-related polyarteritis nodosa, who failed treatment with corticosteroids. Improvement in gait and a marked decrease in serum creatinine, respectively, were observed within 24 h of the first dose of IVIG. Both patients remained stable for several months. We conclude that IVIG should be considered in patients with vasculitis who fail corticosteroids, or when a rapid response is required. FAU - Boman, S AU - Boman S AD - Department of Internal Medicine, University of Nevada School of Medicine, Las Vegas, USA. FAU - Ballen, J L AU - Ballen JL FAU - Seggev, J S AU - Seggev JS LA - eng PT - Case Reports PT - Journal Article PL - England TA - J Intern Med JT - Journal of internal medicine JID - 8904841 RN - 0 (Immunoglobulins, Intravenous) SB - IM MH - Adult MH - Female MH - Humans MH - Immunoglobulins, Intravenous/*therapeutic use MH - Male MH - Vasculitis/*drug therapy EDAT- 1995/10/01 00:00 MHDA- 1995/10/01 00:01 CRDT- 1995/10/01 00:00 PHST- 1995/10/01 00:00 [pubmed] PHST- 1995/10/01 00:01 [medline] PHST- 1995/10/01 00:00 [entrez] AID - 10.1111/j.1365-2796.1995.tb01213.x [doi] PST - ppublish SO - J Intern Med. 1995 Oct;238(4):375-7. doi: 10.1111/j.1365-2796.1995.tb01213.x.