PMID- 7606925 OWN - NLM STAT- MEDLINE DCOM- 19950816 LR - 20180214 IS - 0301-0171 (Print) IS - 0301-0171 (Linking) VI - 71 IP - 1 DP - 1995 TI - Lysosomal chitobiase (CTB) and the G-protein gamma 5 subunit (GNG5) genes co-localize to human chromosome 1p22. PG - 44-6 AB - Previously isolated human placental cDNA clones represent a fusion of specific RNA sequences encoded by two genes: lysosomal chitobiase (CTB) and G-protein gamma 5 subunit (GNG5, Fisher and Aronson, 1992a, 1992b). Both genes have now been mapped to 1p by PCR analysis of somatic cell hybrids and further refined to 1p22 by fluorescence in situ hybridization (FISH) using a YAC clone that contains both the chitobiase and gamma 5 genes. FAU - Ahmad, W AU - Ahmad W AD - Department of Biochemistry and Molecular Biology, College of Medicine, University of South Alabama, Mobile 36688-0002, USA. FAU - Li, S AU - Li S FAU - Chen, H AU - Chen H FAU - Tuck-Muller, C M AU - Tuck-Muller CM FAU - Pittler, S J AU - Pittler SJ FAU - Aronson, N N Jr AU - Aronson NN Jr LA - eng GR - DK-33314/DK/NIDDK NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - Switzerland TA - Cytogenet Cell Genet JT - Cytogenetics and cell genetics JID - 0367735 RN - 0 (DNA Primers) RN - EC 3.2.1.52 (Acetylglucosaminidase) RN - EC 3.6.1.- (GTP-Binding Proteins) SB - IM GS - CTB GS - GNG5 MH - Acetylglucosaminidase/*genetics MH - Base Sequence MH - Chromosome Mapping MH - *Chromosomes, Human, Pair 1 MH - DNA Primers MH - GTP-Binding Proteins/*genetics MH - Humans MH - In Situ Hybridization, Fluorescence MH - Lysosomes/*enzymology MH - Molecular Sequence Data MH - Polymerase Chain Reaction EDAT- 1995/01/01 00:00 MHDA- 2001/03/28 10:01 CRDT- 1995/01/01 00:00 PHST- 1995/01/01 00:00 [pubmed] PHST- 2001/03/28 10:01 [medline] PHST- 1995/01/01 00:00 [entrez] AID - 10.1159/000134059 [doi] PST - ppublish SO - Cytogenet Cell Genet. 1995;71(1):44-6. doi: 10.1159/000134059.