PMID- 7606930 OWN - NLM STAT- MEDLINE DCOM- 19950816 LR - 20180214 IS - 0301-0171 (Print) IS - 0301-0171 (Linking) VI - 71 IP - 1 DP - 1995 TI - Localization of the Chinese hamster MHC locus to chromosome 1q17-->q18 by fluorescence in situ hybridization. PG - 62-3 AB - Comparative gene mapping analysis in mammals suggests that the major histocompatibility complex (MHC) genes map syntenic with genes, such as glyoxylase 1 (GLO1). In man, the MHC locus and other genes of this syntenic group map to chromosome band 6p21.3, and in mouse, these genes map to chromosome 17. In the hamster, however, only the GLO1 gene has been localized; GLO1 maps to chromosome 1, suggesting that the genes within the MHC locus also map to this chromosome. We have localized the hamster MHC class I genes to chromosome band 1q17-->q18 by fluorescence in situ hybridization (FISH). These results suggest that GLO1 and other syntenic genes also lie within this chromosome region. FAU - Rassool, F V AU - Rassool FV AD - Section of Hematology/Oncology, University of Chicago, IL, USA. FAU - Neilly, M E AU - Neilly ME FAU - McGuire, K L AU - McGuire KL FAU - McKeithan, T W AU - McKeithan TW FAU - Le Beau, M M AU - Le Beau MM LA - eng GR - CA40046/CA/NCI NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - Switzerland TA - Cytogenet Cell Genet JT - Cytogenetics and cell genetics JID - 0367735 SB - IM MH - Animals MH - Cell Line MH - Chromosome Mapping MH - Cricetinae MH - In Situ Hybridization, Fluorescence MH - *Major Histocompatibility Complex MH - Mesocricetus/*genetics EDAT- 1995/01/01 00:00 MHDA- 1995/01/01 00:01 CRDT- 1995/01/01 00:00 PHST- 1995/01/01 00:00 [pubmed] PHST- 1995/01/01 00:01 [medline] PHST- 1995/01/01 00:00 [entrez] AID - 10.1159/000134064 [doi] PST - ppublish SO - Cytogenet Cell Genet. 1995;71(1):62-3. doi: 10.1159/000134064.