PMID- 7620951 OWN - NLM STAT- MEDLINE DCOM- 19950831 LR - 20190920 IS - 1078-5884 (Print) IS - 1078-5884 (Linking) VI - 9 IP - 3 DP - 1995 Apr TI - Pharmacological prophylaxis against postoperative graft occlusion after peripheral vascular surgery: a world-wide survey. PG - 267-71 AB - OBJECTIVES: To define current practice regarding the use of pharmacological prophylaxis to prevent postoperative graft occlusion. DESIGN: Prospective open questionnaire. MATERIALS AND METHODS: Questionnaires regarding this subject were sent to vascular surgeons throughout the world to analyse current practice. RESULTS: 651 questionnaires were returned with a response rate of 62% and form the basis for this report. Data from 100,334 vascular reconstructions were reported in this survey. Prophylaxis against postoperative graft occlusions was common. Treatment periods were usually greater than 1 year. Among carotid surgery patients, 82% received prophylaxis, consisting mainly of low-dose acetysalicylic acid (ASA). In Mid-Europe the use of oral anticoagulation was more common than in other regions (p < 0.001). Among aneurysm surgery patients, 38% received prophylaxis. For infrainguinal bypass, ASA in low dose was the most commonly used agent worldwide. However, oral anticoagulation was more frequent in Mid-Europe, in contrast to South America where the combination of ASA and dipyridamole was most common. Considerable geographical differences regarding patient selection, the frequency of specific procedures and operative techniques existed. CONCLUSIONS: Important world-wide differences exist regarding prophylaxis for postoperative graft occlusion. FAU - Lindblad, B AU - Lindblad B AD - Department of Surgery, Lund University, Malmo General Hospital, Sweden. FAU - Wakefield, T W AU - Wakefield TW FAU - Stanley, T J AU - Stanley TJ FAU - Bergqvist, D AU - Bergqvist D FAU - Nichol, B J AU - Nichol BJ FAU - Greenfield, L J AU - Greenfield LJ FAU - Stanley, J C AU - Stanley JC FAU - Bergentz, S E AU - Bergentz SE LA - eng PT - Journal Article PL - England TA - Eur J Vasc Endovasc Surg JT - European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery JID - 9512728 RN - 0 (Anticoagulants) RN - 64ALC7F90C (Dipyridamole) RN - OM90ZUW7M1 (Ticlopidine) RN - R16CO5Y76E (Aspirin) SB - IM MH - Anticoagulants/*therapeutic use MH - Aspirin/*therapeutic use MH - Data Collection MH - Dipyridamole/therapeutic use MH - Drug Utilization/statistics & numerical data MH - Graft Occlusion, Vascular/*prevention & control MH - Humans MH - Peripheral Vascular Diseases/*surgery MH - *Practice Patterns, Physicians' MH - Societies, Medical MH - Ticlopidine/therapeutic use MH - Time Factors MH - Vascular Surgical Procedures/statistics & numerical data EDAT- 1995/04/01 00:00 MHDA- 1995/04/01 00:01 CRDT- 1995/04/01 00:00 PHST- 1995/04/01 00:00 [pubmed] PHST- 1995/04/01 00:01 [medline] PHST- 1995/04/01 00:00 [entrez] AID - S1078-5884(05)80129-7 [pii] AID - 10.1016/s1078-5884(05)80129-7 [doi] PST - ppublish SO - Eur J Vasc Endovasc Surg. 1995 Apr;9(3):267-71. doi: 10.1016/s1078-5884(05)80129-7.