PMID- 7630626
OWN - NLM
STAT- MEDLINE
DCOM- 19950907
LR  - 20180217
IS  - 0030-3755 (Print)
IS  - 0030-3755 (Linking)
VI  - 209
IP  - 3
DP  - 1995
TI  - Elevated anti-neutrophil cytoplasmic antibody titer in a patient with atypical 
      orbital pseudotumor.
PG  - 172-5
AB  - We recently examined a patient with ophthalmic manifestations of Wegener's 
      granulomatosis in whom antineutrophil cytoplasmic antibody (cANCA) titers 
      provided helpful diagnostic information. A 40-year-old man who had suffered from 
      bilateral exophthalmos for 9 months was diagnosed initially as having idiopathic 
      inflammatory pseudotumor. The patient exhibited purulent nasal discharge and 
      microhematuria. A histopathologic study revealed vasculitis. His ANCA titer for 
      cANCA was found to be evaluated, and our patient was subsequently diagnosed as 
      having Wegener's granulomatosis. His ocular symptoms resolved and did not recur 
      after treatment with corticosteroid in combination with cyclophosphamide. We 
      believe that cANCA levels should be investigated in patients with orbital 
      pseudotumor as a possible sign of Wegener's granulomatosis.
FAU - Yamashita, K
AU  - Yamashita K
AD  - Third Department of Internal Medicine, Shimane Medical University, Japan.
FAU - Kobayashi, S
AU  - Kobayashi S
FAU - Kondo, M
AU  - Kondo M
FAU - Ishikura, H
AU  - Ishikura H
FAU - Shibuya, Y
AU  - Shibuya Y
FAU - Hayasaka, S
AU  - Hayasaka S
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Switzerland
TA  - Ophthalmologica
JT  - Ophthalmologica. Journal international d'ophtalmologie. International journal of 
      ophthalmology. Zeitschrift fur Augenheilkunde
JID - 0054655
RN  - 0 (Antibodies, Antineutrophil Cytoplasmic)
RN  - 0 (Autoantibodies)
RN  - 0 (Biomarkers)
SB  - IM
MH  - Adult
MH  - Antibodies, Antineutrophil Cytoplasmic
MH  - Autoantibodies/*analysis
MH  - Biomarkers
MH  - Exophthalmos/diagnosis
MH  - Fluorescein Angiography
MH  - Fundus Oculi
MH  - Granulomatosis with Polyangiitis/*diagnosis
MH  - Humans
MH  - Male
MH  - Orbit/diagnostic imaging/pathology
MH  - Orbital Pseudotumor/*diagnosis
MH  - Retinal Vessels/pathology
MH  - Tomography, X-Ray Computed
MH  - Vasculitis/diagnosis
EDAT- 1995/01/01 00:00
MHDA- 1995/01/01 00:01
CRDT- 1995/01/01 00:00
PHST- 1995/01/01 00:00 [pubmed]
PHST- 1995/01/01 00:01 [medline]
PHST- 1995/01/01 00:00 [entrez]
AID - 10.1159/000310606 [doi]
PST - ppublish
SO  - Ophthalmologica. 1995;209(3):172-5. doi: 10.1159/000310606.