PMID- 7640654
OWN - NLM
STAT- MEDLINE
DCOM- 19950921
LR  - 20181130
IS  - 1065-6995 (Print)
IS  - 1065-6995 (Linking)
VI  - 19
IP  - 5
DP  - 1995 May
TI  - Transforming growth factor alpha.
PG  - 373-88
AB  - Transforming growth factor alpha (TGF alpha) is a close relative of epidermal 
      growth factor (EGF), the first polypeptide mitogen discovered in 1962 (Cohen, 
      1962). TGF alpha, like EGF, exerts its effect on cells through binding to the 
      EGF-Receptor (EGF-R). Here we review the molecular and cell biology of TGF alpha 
      before proceeding to describe our own work on signaling molecules induced in 
      response to activation of the EGF-R.
FAU - Kumar, V
AU  - Kumar V
AD  - Academic Surgical Unit, London Hospital Medical College, UK.
FAU - Bustin, S A
AU  - Bustin SA
FAU - McKay, I A
AU  - McKay IA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Cell Biol Int
JT  - Cell biology international
JID - 9307129
RN  - 0 (Transforming Growth Factor alpha)
RN  - 62229-50-9 (Epidermal Growth Factor)
RN  - EC 2.7.10.1 (ErbB Receptors)
RN  - EC 3.6.5.2 (ras Proteins)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Cell Transformation, Neoplastic
MH  - Epidermal Growth Factor/chemistry
MH  - ErbB Receptors/*physiology
MH  - Humans
MH  - Models, Biological
MH  - Molecular Sequence Data
MH  - Protein Structure, Secondary
MH  - Psoriasis/pathology/physiopathology
MH  - Signal Transduction
MH  - Transforming Growth Factor alpha/chemistry/genetics/*physiology
MH  - ras Proteins/physiology
RF  - 107
EDAT- 1995/05/01 00:00
MHDA- 1995/05/01 00:01
CRDT- 1995/05/01 00:00
PHST- 1995/05/01 00:00 [pubmed]
PHST- 1995/05/01 00:01 [medline]
PHST- 1995/05/01 00:00 [entrez]
AID - S1065-6995(85)71083-9 [pii]
AID - 10.1006/cbir.1995.1083 [doi]
PST - ppublish
SO  - Cell Biol Int. 1995 May;19(5):373-88. doi: 10.1006/cbir.1995.1083.