PMID- 7647420 OWN - NLM STAT- MEDLINE DCOM- 19950926 LR - 20190516 IS - 0918-2918 (Print) IS - 0918-2918 (Linking) VI - 34 IP - 5 DP - 1995 May TI - Primary biliary cirrhosis (PBC)-CREST (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly and telangiectasia) overlap syndrome complicated by Sjogren's syndrome and arthritis. PG - 451-4 AB - A 36-year-old woman with primary biliary cirrhosis (PBC)-CREST (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly and telangiectasia) overlap syndrome complicated by Sjogren's syndrome and arthritis is reported. She had suffered from Raynaud's phenomenon, sclerodactyly, morning stiffness, arthralgia and sicca symptoms since 34 years of age. She exhibited an increased level of alkaline phosphatase and hyperglobulinemia at 2.8 g/dl without any symptoms, and histological findings from the biopsy specimen of the liver were consistent with those of PBC. Her human leukocyte antigen (HLA) typing was DR8 homozygous. FAU - Ito, M AU - Ito M AD - Department of Internal Medicine II, Fukushima Medical College. FAU - Kojima, T AU - Kojima T FAU - Miyata, M AU - Miyata M FAU - Saka, M AU - Saka M FAU - Kokubun, M AU - Kokubun M FAU - Ohira, H AU - Ohira H FAU - Ishikawa, H AU - Ishikawa H FAU - Kuroda, M AU - Kuroda M FAU - Sato, Y AU - Sato Y FAU - Takagi, T AU - Takagi T AU - et al. LA - eng PT - Case Reports PT - Journal Article PL - Japan TA - Intern Med JT - Internal medicine (Tokyo, Japan) JID - 9204241 RN - 0 (HLA-DR Antigens) RN - 0 (HLA-DR Serological Subtypes) RN - 0 (HLA-DR8 antigen) SB - IM MH - Adult MH - Arthritis/*complications/immunology MH - CREST Syndrome/*complications/immunology MH - Female MH - HLA-DR Antigens/analysis/immunology MH - HLA-DR Serological Subtypes MH - Histocompatibility Testing MH - Humans MH - Liver Cirrhosis, Biliary/*complications/immunology MH - Pedigree MH - Sjogren's Syndrome/*complications/immunology EDAT- 1995/05/01 00:00 MHDA- 1995/05/01 00:01 CRDT- 1995/05/01 00:00 PHST- 1995/05/01 00:00 [pubmed] PHST- 1995/05/01 00:01 [medline] PHST- 1995/05/01 00:00 [entrez] AID - 10.2169/internalmedicine.34.451 [doi] PST - ppublish SO - Intern Med. 1995 May;34(5):451-4. doi: 10.2169/internalmedicine.34.451.