PMID- 7655733
OWN - NLM
STAT- MEDLINE
DCOM- 19951002
LR  - 20190920
IS  - 0945-6317 (Print)
IS  - 0945-6317 (Linking)
VI  - 426
IP  - 6
DP  - 1995
TI  - Multiple endocrine neoplasia type 1 (MEN 1) revisited.
PG  - 541-8
AB  - Multiple endocrine neoplasia type 1 (MEN 1) is an inherited disease of the 
      neuroendocrine cell system affecting primarily the parathyroids, pancreas, 
      duodenum and the anterior pituitary. The pancreatic and duodenal tumours may 
      metastasize, but generally have a low malignant potential. The diagnosis of MEN 1 
      is usually made in the second decade of life and based on the involvement of at 
      least two organs and a family history. The recent discovery of the MEN 1 locus on 
      the centromeric region of the long arm of chromosome 11 may become a further 
      diagnostic criterion. The use of flanking DNA markers permits presymptomatic 
      testing for MEN 1 in affected families.
FAU - Padberg, B
AU  - Padberg B
AD  - Department of Pathology, University of Zurich, Switzerland.
FAU - Schroder, S
AU  - Schroder S
FAU - Capella, C
AU  - Capella C
FAU - Frilling, A
AU  - Frilling A
FAU - Kloppel, G
AU  - Kloppel G
FAU - Heitz, P U
AU  - Heitz PU
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - Germany
TA  - Virchows Arch
JT  - Virchows Archiv : an international journal of pathology
JID - 9423843
SB  - IM
MH  - Age Factors
MH  - Humans
MH  - Multiple Endocrine Neoplasia Type 1/complications/genetics/*pathology
MH  - Prognosis
RF  - 93
EDAT- 1995/01/01 00:00
MHDA- 1995/01/01 00:01
CRDT- 1995/01/01 00:00
PHST- 1995/01/01 00:00 [pubmed]
PHST- 1995/01/01 00:01 [medline]
PHST- 1995/01/01 00:00 [entrez]
AID - 10.1007/BF00192107 [doi]
PST - ppublish
SO  - Virchows Arch. 1995;426(6):541-8. doi: 10.1007/BF00192107.