PMID- 7656591 OWN - NLM STAT- MEDLINE DCOM- 19951004 LR - 20180214 IS - 0301-0171 (Print) IS - 0301-0171 (Linking) VI - 71 IP - 2 DP - 1995 TI - FISH on metaphase and interphase chromosomes demonstrates the physical order of the genes for GPI, CRC, and LIPE in pigs. PG - 175-8 AB - The porcine genes for glucose phosphate isomerase (GPI), calcium release channel (CRC), and hormone-sensitive lipase (LIPE) map to the long arm of chromosome 6. Earlier studies, using fluorescence in situ hybridization (FISH), mapped the three loci to the same band, viz., 6q12. To ascertain the relative order of the three genes, we first conducted three double-color FISH experiments, cohybridizing two of the probes at a time. These experiments demonstrated that the gene order was cen-GPI-CRC-LIPE. This order was confirmed by cohybridizing the three probes to both metaphase and interphase chromosomes. FAU - Chowdhary, B P AU - Chowdhary BP AD - Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala. FAU - de la Sena, C AU - de la Sena C FAU - Harbitz, I AU - Harbitz I FAU - Eriksson, L AU - Eriksson L FAU - Gustavsson, I AU - Gustavsson I LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Switzerland TA - Cytogenet Cell Genet JT - Cytogenetics and cell genetics JID - 0367735 RN - 0 (DNA Probes) SB - IM GS - CRC GS - GPI GS - LIPE MH - Animals MH - Chromosomes/*genetics MH - DNA Probes MH - In Situ Hybridization, Fluorescence MH - Interphase MH - Metaphase MH - Swine/*genetics EDAT- 1995/01/01 00:00 MHDA- 1995/01/01 00:01 CRDT- 1995/01/01 00:00 PHST- 1995/01/01 00:00 [pubmed] PHST- 1995/01/01 00:01 [medline] PHST- 1995/01/01 00:00 [entrez] AID - 10.1159/000134101 [doi] PST - ppublish SO - Cytogenet Cell Genet. 1995;71(2):175-8. doi: 10.1159/000134101.