PMID- 7656822 OWN - NLM STAT- MEDLINE DCOM- 19951004 LR - 20071115 IS - 0253-3766 (Print) IS - 0253-3766 (Linking) VI - 17 IP - 3 DP - 1995 May TI - [Detection of chromosome aberrations in peripheral T-cell lymphomas by fluorescence in situ hybridization]. PG - 187-90 AB - Using fluorescence in situ hybridization (FISH) technique, we have detected trisomy 3(+3) and gain of an extra X chromosome (+X) in 32 (78%) and 14 (34%) of 41 patients with peripheral T-cell lymphomas, respectively. However, cells with trisomy 3 and +X were, on average, 4.5% and 8.2%, respectively. The study showed that trisomy 3 and +X were the specific chromosome aberrations of peripheral T-cell lymphoma; cells with +3 and +X constituted only a small part in a specimen: FISH was more sensitive than traditional cytogenetics in detection of chromosome aberrations. FAU - Zhang, Y AU - Zhang Y AD - Zhejiang Medical University, Hangzhou. LA - chi PT - English Abstract PT - Journal Article PL - China TA - Zhonghua Zhong Liu Za Zhi JT - Zhonghua zhong liu za zhi [Chinese journal of oncology] JID - 7910681 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - *Chromosome Aberrations MH - Female MH - Humans MH - Immunoblastic Lymphadenopathy/genetics MH - In Situ Hybridization, Fluorescence MH - Lymphoma, Non-Hodgkin/genetics MH - Lymphoma, T-Cell, Peripheral/*genetics MH - Male MH - Middle Aged MH - Trisomy MH - X Chromosome EDAT- 1995/05/01 00:00 MHDA- 1995/05/01 00:01 CRDT- 1995/05/01 00:00 PHST- 1995/05/01 00:00 [pubmed] PHST- 1995/05/01 00:01 [medline] PHST- 1995/05/01 00:00 [entrez] PST - ppublish SO - Zhonghua Zhong Liu Za Zhi. 1995 May;17(3):187-90.