PMID- 7657311
OWN - NLM
STAT- MEDLINE
DCOM- 19950929
LR  - 20190821
IS  - 0309-0167 (Print)
IS  - 0309-0167 (Linking)
VI  - 26
IP  - 5
DP  - 1995 May
TI  - Demonstration of the Philadelphia translocation by fluorescence in situ 
      hybridization (FISH) in paraffin sections and identification of aberrant cells by 
      a combined FISH/immunophenotyping approach.
PG  - 433-7
AB  - The Philadelphia translocation was demonstrated by two-colour fluorescence in 
      situ hybridization (FISH) in decalcified paraffin sections of bone marrow from 
      patients with chronic myelogenous leukaemia. FISH was combined with 
      immunocytochemical detection of different membrane-bound or cytoplasmic antigens. 
      With this new technique, the cells bearing the 9:22 translocation can be 
      identified morphologically, as well as immunocytochemically, in tissue sections.
FAU - Nolte, M
AU  - Nolte M
AD  - Pathologisches Institut, Medizinischen Hochschule Hannover, Germany.
FAU - Werner, M
AU  - Werner M
FAU - Ewig, M
AU  - Ewig M
FAU - von Wasielewski, R
AU  - von Wasielewski R
FAU - Wilkens, L
AU  - Wilkens L
FAU - Georgii, A
AU  - Georgii A
LA  - eng
PT  - Journal Article
PL  - England
TA  - Histopathology
JT  - Histopathology
JID - 7704136
RN  - 0 (Antigens, CD)
RN  - 0 (Antigens, Differentiation, Myelomonocytic)
RN  - 0 (Antigens, Neoplasm)
RN  - 0 (CD68 antigen, human)
RN  - 0 (DNA, Neoplasm)
RN  - 0 (Vimentin)
RN  - 0 (von Willebrand Factor)
RN  - EC 3.1.3.48 (Leukocyte Common Antigens)
SB  - IM
GS  - abl
GS  - bcr
MH  - Antigens, CD/analysis
MH  - Antigens, Differentiation, Myelomonocytic/analysis
MH  - Antigens, Neoplasm/immunology
MH  - Bone Marrow/ultrastructure
MH  - DNA, Neoplasm/analysis
MH  - Humans
MH  - *Immunophenotyping
MH  - *In Situ Hybridization, Fluorescence
MH  - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*genetics/pathology
MH  - Leukocyte Common Antigens/analysis
MH  - *Paraffin Embedding
MH  - *Philadelphia Chromosome
MH  - Vimentin/analysis
MH  - von Willebrand Factor/analysis
EDAT- 1995/05/01 00:00
MHDA- 1995/05/01 00:01
CRDT- 1995/05/01 00:00
PHST- 1995/05/01 00:00 [pubmed]
PHST- 1995/05/01 00:01 [medline]
PHST- 1995/05/01 00:00 [entrez]
AID - 10.1111/j.1365-2559.1995.tb00250.x [doi]
PST - ppublish
SO  - Histopathology. 1995 May;26(5):433-7. doi: 10.1111/j.1365-2559.1995.tb00250.x.