PMID- 7659582
OWN - NLM
STAT- MEDLINE
DCOM- 19951002
LR  - 20190726
IS  - 0147-8389 (Print)
IS  - 0147-8389 (Linking)
VI  - 18
IP  - 6
DP  - 1995 Jun
TI  - Familial atrioventricular heart block of adult onset: electrocardiogram and HLA 
      typing analysis.
PG  - 1276-8
AB  - A family was investigated because of heart block and sinus arrhythmia. The 
      electrical characteristics were: (1) adult onset in all members; (2) complete 
      heart block with atrial fibrillation in 2, and first- or second-degree heart 
      block in 7 members; and (3) sinus arrhythmia in 3 members. Human leukocyte 
      antigen (HLA) typing was performed. HLA A2, B39, Cw7, and DR12 were positive in 4 
      of 5 members in the heart block group. In the sinus arrhythmia group, HLA DR12 
      was positive in all members. In the normal group, none of these HLA typings was 
      positive except one. These findings indicate a tighter relationship between heart 
      block and the HLA locus than previously thought.
FAU - Ebisawa, K
AU  - Ebisawa K
AD  - Department of Cardiology, Jichi Medical School, Tochigi, Japan.
FAU - Nakayama, T
AU  - Nakayama T
FAU - Tanaka, K
AU  - Tanaka K
FAU - Shimada, K
AU  - Shimada K
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Pacing Clin Electrophysiol
JT  - Pacing and clinical electrophysiology : PACE
JID - 7803944
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Adult
MH  - Age of Onset
MH  - Aged
MH  - Aged, 80 and over
MH  - Arrhythmia, Sinus/diagnosis/epidemiology/genetics
MH  - Atrial Fibrillation/diagnosis/epidemiology/genetics
MH  - Electrocardiography
MH  - Female
MH  - HLA Antigens/*genetics
MH  - Heart Block/diagnosis/epidemiology/*genetics
MH  - Histocompatibility Testing
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pedigree
EDAT- 1995/06/01 00:00
MHDA- 1995/06/01 00:01
CRDT- 1995/06/01 00:00
PHST- 1995/06/01 00:00 [pubmed]
PHST- 1995/06/01 00:01 [medline]
PHST- 1995/06/01 00:00 [entrez]
AID - 10.1111/j.1540-8159.1995.tb06968.x [doi]
PST - ppublish
SO  - Pacing Clin Electrophysiol. 1995 Jun;18(6):1276-8. doi: 
      10.1111/j.1540-8159.1995.tb06968.x.