PMID- 7662489
OWN - NLM
STAT- MEDLINE
DCOM- 19951012
LR  - 20190920
IS  - 0914-7187 (Print)
IS  - 0914-7187 (Linking)
VI  - 9
IP  - 2
DP  - 1995 May
TI  - Scintigraphic detection of recurrence of medullary thyroid cancer.
PG  - 101-4
AB  - A case of recurrent medullary thyroid cancer (MTC) was evaluated with 123I-MIBG, 
      99mTc(V)-dimercaptosuccinic acid (DMSA), and 201Tl scintigraphy. This patient had 
      been operated on for MTC in the right thyroid. Recently a left neck mass was 
      noticed, and was suspected of being a recurrence of MTC based on increased plasma 
      calcitonin (CT) and carcinoembryonic antigen (CEA). He was operated on for the 
      neck mass which revealed MTC, and papillary thyroid cancer was incidentally found 
      in the left thyroid, but the CT and CEA levels remained high, and remaining MTC 
      tumor was suspected. But the location of the tumor was unknown. Although 
      99mTc(V)-DMSA scintigraphy is generally believed to be superior in sensitivity to 
      123I-MIBG scintigraphy, it did not demonstrate the tumor site but 201Tl and 
      123I-MIBG did. Furthermore, 123I-MIBG scintigraphy has greater specificity for 
      tumors which arise in the neural crest. Judging from the results of this case and 
      cases reported in the literatures, both 123I-MIBG and 99mTc(V)-DMSA should be 
      performed in the detection of recurrent MTC.
FAU - Koizumi, M
AU  - Koizumi M
AD  - Department of Nuclear Medicine, Cancer Institute Hospital, Tokyo, Japan.
FAU - Yamada, Y
AU  - Yamada Y
FAU - Nomura, E
AU  - Nomura E
FAU - Amano, M
AU  - Amano M
FAU - Okajima, Y
AU  - Okajima Y
FAU - Okizuka, H
AU  - Okizuka H
FAU - Yamada, K
AU  - Yamada K
FAU - Sawano, S
AU  - Sawano S
FAU - Kitahara, T
AU  - Kitahara T
FAU - Yamashita, T
AU  - Yamashita T
AU  - et al.
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Ann Nucl Med
JT  - Annals of nuclear medicine
JID - 8913398
RN  - 0 (Iodobenzenes)
RN  - 35MRW7B4AD (3-Iodobenzylguanidine)
RN  - DX1U2629QE (Succimer)
SB  - IM
MH  - 3-Iodobenzylguanidine
MH  - Humans
MH  - Iodobenzenes
MH  - Male
MH  - Middle Aged
MH  - Radionuclide Imaging
MH  - Recurrence
MH  - Succimer
MH  - Thyroid Neoplasms/*diagnostic imaging
EDAT- 1995/05/01 00:00
MHDA- 1995/05/01 00:01
CRDT- 1995/05/01 00:00
PHST- 1995/05/01 00:00 [pubmed]
PHST- 1995/05/01 00:01 [medline]
PHST- 1995/05/01 00:00 [entrez]
AID - 10.1007/BF03164975 [doi]
PST - ppublish
SO  - Ann Nucl Med. 1995 May;9(2):101-4. doi: 10.1007/BF03164975.