PMID- 7665687 OWN - NLM STAT- MEDLINE DCOM- 19951012 LR - 20210526 IS - 0095-1137 (Print) IS - 1098-660X (Electronic) IS - 0095-1137 (Linking) VI - 33 IP - 7 DP - 1995 Jul TI - Human herpesviruses 6 and 7 in cervixes of pregnant women. PG - 1968-70 AB - We looked for human herpesvirus 6 (HHV-6) and HHV-7 genomes in the cervixes of pregnant women in the late stages of their pregnancies. Of 72 samples collected with cervical swabs and amplified by nested PCR, we found that 14 (19.4%) and 2 (2.7%) contained detectable HHV-6 and HHV-7 genomes, respectively. The two samples in which HHV-7 DNA was detected also contained HHV-6 genomes. Hybridization of HHV-6 DNA amplified by PCR with variant-specific probes revealed that all of these DNA samples belonged to variant type B. These results indicated that HHV-6 and/or HHV-7 exists in the cervixes of infected women in late pregnancy and may cause perinatal infection. FAU - Okuno, T AU - Okuno T AD - Public Health Research Institute, Kobe City, Japan. FAU - Oishi, H AU - Oishi H FAU - Hayashi, K AU - Hayashi K FAU - Nonogaki, M AU - Nonogaki M FAU - Tanaka, K AU - Tanaka K FAU - Yamanishi, K AU - Yamanishi K LA - eng PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article PL - United States TA - J Clin Microbiol JT - Journal of clinical microbiology JID - 7505564 RN - 0 (DNA Primers) RN - 0 (DNA Probes) RN - 0 (DNA, Viral) SB - IM MH - Base Sequence MH - Cervix Uteri/*virology MH - DNA Primers/genetics MH - DNA Probes/genetics MH - DNA, Viral/genetics MH - Female MH - Herpesviridae Infections/*complications/transmission/virology MH - Herpesvirus 6, Human/genetics/*isolation & purification MH - Herpesvirus 7, Human/genetics/*isolation & purification MH - Humans MH - Infant, Newborn MH - Infectious Disease Transmission, Vertical MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - Pregnancy MH - Pregnancy Complications, Infectious/*virology PMC - PMC228316 EDAT- 1995/07/01 00:00 MHDA- 1995/07/01 00:01 PMCR- 1995/07/01 CRDT- 1995/07/01 00:00 PHST- 1995/07/01 00:00 [pubmed] PHST- 1995/07/01 00:01 [medline] PHST- 1995/07/01 00:00 [entrez] PHST- 1995/07/01 00:00 [pmc-release] AID - 10.1128/jcm.33.7.1968-1970.1995 [doi] PST - ppublish SO - J Clin Microbiol. 1995 Jul;33(7):1968-70. doi: 10.1128/jcm.33.7.1968-1970.1995.