PMID- 7667047
OWN - NLM
STAT- MEDLINE
DCOM- 19951011
LR  - 20061115
IS  - 0031-2991 (Print)
IS  - 0031-2991 (Linking)
IP  - 2
DP  - 1995 Apr-Jun
TI  - [Effect of anti-histone antibodies on the nuclear apparatus of thymocytes of 
      intact and irradiated rats].
PG  - 7-9
AB  - The interaction of specific immunoglobulins G to the histone H1 with the 
      thymocytes of intact animals has been demonstrated to increase the reception of 
      acridine orange (AO) in nuclear chromatin. This raises the rate of AO 
      fluorescence and lowers the level of light polarization. This may result from 
      occurring decondensation processes. On the other hand, the interaction of 
      antihistone antibodies with irradiated rat thymocytes causes no changes in the 
      package of nuclear chromatin, which is likely to be due to destructive processes 
      which take place in the cells in response to radiation. The immunoglobulins G to 
      the core histone H2B produce an insignificant effect on the condensation rate of 
      the nuclear material of thymocytes both from intact and irradiated animals.
FAU - Zaichik, A Sh
AU  - Zaichik ASh
FAU - Babichev, A V
AU  - Babichev AV
FAU - Reshchikov, A M
AU  - Reshchikov AM
FAU - Mamedova, G V
AU  - Mamedova GV
LA  - rus
PT  - English Abstract
PT  - Journal Article
TT  - Issledovanie vliianiia antigistonovykh antitel na iaderni apparat timotsitov 
      intaktnykh i obluchennykh krys.
PL  - Russia (Federation)
TA  - Patol Fiziol Eksp Ter
JT  - Patologicheskaia fiziologiia i eksperimental'naia terapiia
JID - 0376421
RN  - 0 (Histones)
RN  - 0 (Immunoglobulin G)
SB  - IM
MH  - Animals
MH  - Cell Nucleus/*immunology/radiation effects
MH  - Histones/*immunology
MH  - *Immunoglobulin G
MH  - Rats
MH  - Rats, Wistar
MH  - Thymus Gland/cytology/*immunology/radiation effects
EDAT- 1995/04/01 00:00
MHDA- 1995/04/01 00:01
CRDT- 1995/04/01 00:00
PHST- 1995/04/01 00:00 [pubmed]
PHST- 1995/04/01 00:01 [medline]
PHST- 1995/04/01 00:00 [entrez]
PST - ppublish
SO  - Patol Fiziol Eksp Ter. 1995 Apr-Jun;(2):7-9.