PMID- 7669742
OWN - NLM
STAT- MEDLINE
DCOM- 19951018
LR  - 20191023
IS  - 1045-2257 (Print)
IS  - 1045-2257 (Linking)
VI  - 13
IP  - 3
DP  - 1995 Jul
TI  - U937 cell line has a t(10;11)(p13-14;q14-21) rather than a deletion of 11q.
PG  - 217-8
AB  - The U937 cell line was studied with the fluorescence in situ hybridization (FISH) 
      technique using phage and cosmid probes which were mapped and ordered on 11q. 
      Although this cell line was thought to have a del(11q), FISH demonstrated that 
      11q was translocated to 10p and that the breakpoint on 11q is centromeric to the 
      MLL gene. This 10;11 translocation appears to be a t(10;11)(p13-14;q14-21), which 
      was recently reported to be a recurring translocation in malignant hematologic 
      disease. This cell line will be a good tool for the study of this chromosomal 
      rearrangement.
FAU - Kobayashi, H
AU  - Kobayashi H
AD  - Department of Medicine, University of Chicago, IL 60637-1470, USA.
FAU - Thirman, M J
AU  - Thirman MJ
FAU - Rowley, J D
AU  - Rowley JD
LA  - eng
GR  - CA42577/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Genes Chromosomes Cancer
JT  - Genes, chromosomes & cancer
JID - 9007329
SB  - IM
MH  - *Chromosomes, Human, Pair 10
MH  - *Chromosomes, Human, Pair 11
MH  - *Gene Deletion
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - *Translocation, Genetic
MH  - Tumor Cells, Cultured
EDAT- 1995/07/01 00:00
MHDA- 1995/07/01 00:01
CRDT- 1995/07/01 00:00
PHST- 1995/07/01 00:00 [pubmed]
PHST- 1995/07/01 00:01 [medline]
PHST- 1995/07/01 00:00 [entrez]
AID - 10.1002/gcc.2870130312 [doi]
PST - ppublish
SO  - Genes Chromosomes Cancer. 1995 Jul;13(3):217-8. doi: 10.1002/gcc.2870130312.