PMID- 7676898 OWN - NLM STAT- MEDLINE DCOM- 19951013 LR - 20151008 IS - 0029-0203 (Print) IS - 0029-0203 (Linking) VI - 99 IP - 8 DP - 1995 Aug TI - [Seroprevalence of HTLV-I in various ocular diseases in central Japan]. PG - 959-63 AB - Recently human T-cell lymphotropic virus type I (HTLV-I) has been shown to be responsible for a kind of uveitis in southwestern Japan, where HTLV-I infection is highly endemic. To investigate further the association of HTLV-I with various ocular diseases, we studied HTLV-I seroprevalence in 1,350 patients in central Japan, where HTLV-I infection is not endemic. Of 1,350 patients with various ocular diseases, 40 (2.96%) were seropositive for the retrovirus. There was no statistically significant difference in HTLV-I seroprevalence among various ocular diseases. Four of 9 (44.4%) seropositive cases from southwestern Japan developed HTLV-I associated uveitis (HAU), whereas only 2 of 26 (7.7%) seropositive cases from central Japan developed HAU. The difference was statistically significant (p < 0.05). This suggests that the incidence of HAU could be influenced by environmental or hereditary factors. On the other hand, 3 of 7 (42.9%) patients with episcleritis showed HTLV-I infection. FAU - Goto, K AU - Goto K AD - Division of Ophthalmology, Odawara Municipal Hospital, Japan. FAU - Kurita, M AU - Kurita M FAU - Watanabe, N AU - Watanabe N FAU - Ogi, A AU - Ogi A FAU - Iijima, Y AU - Iijima Y FAU - Hanajiri, M AU - Hanajiri M FAU - Saeki, K AU - Saeki K FAU - Ohno, S AU - Ohno S LA - jpn PT - Case Reports PT - English Abstract PT - Journal Article PL - Japan TA - Nippon Ganka Gakkai Zasshi JT - Nippon Ganka Gakkai zasshi JID - 7505716 RN - 0 (HTLV-I Antibodies) SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Base Sequence MH - Child MH - Child, Preschool MH - Eye Diseases/*epidemiology/*immunology MH - Female MH - HTLV-I Antibodies/*analysis MH - HTLV-I Infections/*epidemiology MH - Humans MH - Infant MH - Japan/epidemiology MH - Male MH - Middle Aged MH - Molecular Sequence Data MH - Seroepidemiologic Studies EDAT- 1995/08/01 00:00 MHDA- 1995/08/01 00:01 CRDT- 1995/08/01 00:00 PHST- 1995/08/01 00:00 [pubmed] PHST- 1995/08/01 00:01 [medline] PHST- 1995/08/01 00:00 [entrez] PST - ppublish SO - Nippon Ganka Gakkai Zasshi. 1995 Aug;99(8):959-63.