PMID- 7677237
OWN - NLM
STAT- MEDLINE
DCOM- 19951019
LR  - 20191210
IS  - 0105-4538 (Print)
IS  - 0105-4538 (Linking)
VI  - 50
IP  - 3
DP  - 1995 Mar
TI  - Factors influencing serum immunoglobulin E levels in Greek children.
PG  - 210-4
AB  - Serum levels of immunoglobulin E (IgE) were determined by enzyme immunoassay in 
      414 Greek infants and children of both sexes, 1 month to 14 years old. The 
      children were admitted to the "Aghia Sophia" Teaching Hospital for Children 
      (Athens, Greece) for surgical corrections of minor anatomic abnormalities, but 
      they were otherwise healthy. Statistical analysis was performed through multiple 
      regression after logarithmic transformation of the immunoglobulin values. IgE 
      levels increased significantly by about 80% per year up to the age of 5 years, 
      without noticeable impact of age on these levels thereafter. History of allergic 
      disease showed a significant positive association with serum levels of IgE in 
      both younger (less than 5 years) and older children. History of frequent 
      infections was positively associated with IgE levels, although the relation was 
      statistically significant only in the older age group, IgE levels in Greek 
      children appear to be higher than the corresponding levels of children living in 
      northern Europe, but much lower than those of children in Southeast Asia, a fact 
      that may reflect different exposure level during childhood to infections known to 
      influence IgE levels.
FAU - Petridou, E
AU  - Petridou E
AD  - Department of Hygiene and Epidemiology, Athens University, Medical School, 
      Greece.
FAU - Kanariou, M
AU  - Kanariou M
FAU - Liatsis, M
AU  - Liatsis M
FAU - Spanou, K
AU  - Spanou K
FAU - Revinthi, K
AU  - Revinthi K
FAU - Mandalenaki-Lambrou, K
AU  - Mandalenaki-Lambrou K
FAU - Trichopoulos, D
AU  - Trichopoulos D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Denmark
TA  - Allergy
JT  - Allergy
JID - 7804028
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Age Factors
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Greece/epidemiology
MH  - Humans
MH  - Hypersensitivity/epidemiology/immunology
MH  - Immunoglobulin E/*blood
MH  - Infant
MH  - Infant, Newborn
MH  - Infections/epidemiology/immunology
MH  - Male
MH  - Reference Values
MH  - Regression Analysis
EDAT- 1995/03/01 00:00
MHDA- 1995/03/01 00:01
CRDT- 1995/03/01 00:00
PHST- 1995/03/01 00:00 [pubmed]
PHST- 1995/03/01 00:01 [medline]
PHST- 1995/03/01 00:00 [entrez]
AID - 10.1111/j.1398-9995.1995.tb01135.x [doi]
PST - ppublish
SO  - Allergy. 1995 Mar;50(3):210-4. doi: 10.1111/j.1398-9995.1995.tb01135.x.