PMID- 7683445
OWN - NLM
STAT- MEDLINE
DCOM- 19930603
LR  - 20190825
IS  - 0304-4017 (Print)
IS  - 0304-4017 (Linking)
VI  - 46
IP  - 1-4
DP  - 1993 Feb
TI  - Immunoglobulin E and type I hypersensitivity in bovine ostertagiosis.
PG  - 93-102
AB  - A series of experiments were performed to determine whether immunoglobulin E 
      (IgE) and Type I hypersensitivity reactions might be involved in the immune 
      response of cattle to infection with Ostertagia ostertagi. The following 
      observations were made. (1) When calves were lightly infected, serum IgE levels 
      paralleled worm burdens. However, in heavy infections, both serum and lymph IgE 
      levels were inversely related to burdens of O. ostertagi. (2) Increases in 
      mediators, especially histamine and leukotriene (LT) C4 were detected in tissue 
      or lymph, and were associated with cellular changes indicative of 
      hypersensitivity.
FAU - Baker, D G
AU  - Baker DG
AD  - Department of Veterinary Microbiology & Immunology, School of Veterinary 
      Medicine, University of California, Davis 95616.
FAU - Gershwin, L J
AU  - Gershwin LJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - Netherlands
TA  - Vet Parasitol
JT  - Veterinary parasitology
JID - 7602745
RN  - 0 (Leukotrienes)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Animals
MH  - Antibody Formation
MH  - Cattle
MH  - Cattle Diseases/*immunology
MH  - Histamine Release
MH  - *Hypersensitivity
MH  - Immunoglobulin E/*blood
MH  - Leukotrienes/analysis
MH  - Male
MH  - Orchiectomy
MH  - Ostertagia/immunology/isolation & purification
MH  - Ostertagiasis/immunology/*veterinary
EDAT- 1993/02/01 00:00
MHDA- 1993/02/01 00:01
CRDT- 1993/02/01 00:00
PHST- 1993/02/01 00:00 [pubmed]
PHST- 1993/02/01 00:01 [medline]
PHST- 1993/02/01 00:00 [entrez]
AID - 0304-4017(93)90050-W [pii]
AID - 10.1016/0304-4017(93)90050-w [doi]
PST - ppublish
SO  - Vet Parasitol. 1993 Feb;46(1-4):93-102. doi: 10.1016/0304-4017(93)90050-w.