PMID- 7684721
OWN - NLM
STAT- MEDLINE
DCOM- 19930629
LR  - 20190707
IS  - 0378-1119 (Print)
IS  - 0378-1119 (Linking)
VI  - 127
IP  - 2
DP  - 1993 May 30
TI  - Two neural-cell adhesion molecule (NCAM)-encoding genes in Xenopus laevis are 
      expressed during development and in adult tissues.
PG  - 243-7
AB  - Expression of genes encoding neural-cell adhesion molecules (NCAM) is regulated 
      to a large extent at the level of alternative splicing. Xenopus laevis contains 
      two functional copies of the NCAM gene and comparison of the amino acid sequences 
      of NCAM proteins derived from both genes shows that they differ at approximately 
      8% of positions. Differential expression of these proteins during development or 
      in adult tissues could provide an additional level of regulation above that 
      obtained by alternative splicing. PCR analysis however, shows that both NCAM 
      genes are expressed at similar levels throughout embryonic development and in all 
      adult tissues examined.
FAU - Tonissen, K F
AU  - Tonissen KF
AD  - Department of Zoology, University of Texas, Austin 78712.
FAU - Krieg, P A
AU  - Krieg PA
LA  - eng
SI  - GENBANK/L03653
SI  - GENBANK/L03654
SI  - GENBANK/L07632
SI  - GENBANK/L09602
SI  - GENBANK/M76710
SI  - GENBANK/X54209
SI  - GENBANK/X67280
SI  - GENBANK/X67281
SI  - GENBANK/X67282
SI  - GENBANK/X67283
GR  - HD25179/HD/NICHD NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Gene
JT  - Gene
JID - 7706761
RN  - 0 (Cell Adhesion Molecules, Neuronal)
RN  - 0 (Oligodeoxyribonucleotides)
RN  - 63231-63-0 (RNA)
RN  - 9007-49-2 (DNA)
SB  - IM
GS  - NCAM
MH  - Alternative Splicing
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Cell Adhesion Molecules, Neuronal/*genetics
MH  - Cloning, Molecular
MH  - DNA/genetics/isolation & purification
MH  - Embryo, Nonmammalian/physiology
MH  - Exons
MH  - Female
MH  - Gene Expression
MH  - Gene Expression Regulation
MH  - Molecular Sequence Data
MH  - Oligodeoxyribonucleotides
MH  - Ovum/physiology
MH  - Polymerase Chain Reaction
MH  - RNA/genetics/isolation & purification
MH  - Sequence Homology, Amino Acid
MH  - Xenopus laevis/embryology/*genetics
EDAT- 1993/05/30 00:00
MHDA- 1993/05/30 00:01
CRDT- 1993/05/30 00:00
PHST- 1993/05/30 00:00 [pubmed]
PHST- 1993/05/30 00:01 [medline]
PHST- 1993/05/30 00:00 [entrez]
AID - 0378-1119(93)90727-K [pii]
AID - 10.1016/0378-1119(93)90727-k [doi]
PST - ppublish
SO  - Gene. 1993 May 30;127(2):243-7. doi: 10.1016/0378-1119(93)90727-k.