PMID- 7688600 OWN - NLM STAT- MEDLINE DCOM- 19930913 LR - 20080815 IS - 1121-760X (Print) IS - 1121-760X (Linking) VI - 37 IP - 2 DP - 1993 TI - Heteromorphism of human chromosome 18 detected by fluorescent in situ hybridization. PG - 149-54 AB - The individual variations of pericentromeric heterochromatin in human chromosome 18 were analysed using the C-banding techniques and nonradioactive fluorescence in situ hybridization (FISH) with chromosome 18 alpha-satellite DNA probe. FISH analysis shows heteromorphisms almost undetectable by C-banding and which regularly segregate in a family. FAU - Bonfatti, A AU - Bonfatti A AD - Institute of Medical Genetics USL 31, Ferrara, Italy. FAU - Giunta, C AU - Giunta C FAU - Sensi, A AU - Sensi A FAU - Gruppioni, R AU - Gruppioni R FAU - Rubini, M AU - Rubini M FAU - Fontana, F AU - Fontana F LA - eng PT - Journal Article PL - Italy TA - Eur J Histochem JT - European journal of histochemistry : EJH JID - 9207930 RN - 0 (DNA Probes) RN - 0 (DNA, Satellite) RN - 0 (Heterochromatin) SB - IM MH - Chromosome Banding MH - Chromosomes, Human, Pair 18/*ultrastructure MH - DNA Probes MH - DNA, Satellite/ultrastructure MH - Female MH - Heterochromatin/*ultrastructure MH - Humans MH - In Situ Hybridization MH - Karyotyping MH - Lymphocytes/ultrastructure MH - Male MH - Metaphase MH - Spectrometry, Fluorescence EDAT- 1993/01/01 00:00 MHDA- 1993/01/01 00:01 CRDT- 1993/01/01 00:00 PHST- 1993/01/01 00:00 [pubmed] PHST- 1993/01/01 00:01 [medline] PHST- 1993/01/01 00:00 [entrez] PST - ppublish SO - Eur J Histochem. 1993;37(2):149-54.