PMID- 7691601
OWN - NLM
STAT- MEDLINE
DCOM- 19931108
LR  - 20220318
IS  - 0195-668X (Print)
IS  - 0195-668X (Linking)
VI  - 14
IP  - 8
DP  - 1993 Aug
TI  - Influence of left ventricular filling profile during preceding control beats on 
      the occurrence of pulse deficit caused by ventricular premature contractions.
PG  - 1044-9
AB  - This study was designed to investigate whether the left ventricular filling 
      profile during preceding control beats significantly affects the pulse deficit 
      caused by ventricular premature contractions (VPCs). The study group consisted of 
      18 patients (10 men, eight women, 15-85 years old) who underwent 
      electrophysiological catheterization because of sinus bradycardia. Using a 
      temporary pacing lead inserted in the right ventricular apex, isolated VPCs with 
      various coupling intervals were produced by electrical stimulation of the right 
      ventricle. During the production of the VPCs, the mitral filling flow velocity 
      using pulsed wave Doppler echocardiography, the femoral arterial pressure curve 
      and the electrocardiogram were simultaneously recorded. The right ventricle was 
      stimulated 800, 750, 700, 650, 600, 550, 500, 450 and 400 ms after the triggered 
      control beat QRS complex. Pulse pressures during VPCs gradually decreased in 
      relation to the shortening of the extrasystolic beat coupling interval. The 
      longest coupling interval for each subject, which caused complete abolition of 
      the pressure pulse during the VPC, was defined as the pulse deficit coupling 
      interval. The early to late diastolic velocity-time integral ratio (Ei/Ai ratio) 
      of the mitral filling flow velocity during the control beats which precede the 
      VPC was obtained as an index expressing the left ventricular filling profile. The 
      Ei/Ai ratio of the mitral filling flow velocity ranged from 0.7 to 4.5 (1.8 +/- 
      1.0). The pulse deficit coupling interval ranged from 440 to 640 ms (510 +/- 60 
      ms).(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Otsuji, Y
AU  - Otsuji Y
AD  - First Department of Internal Medicine, Faculty of Medicine, Kagoshima University, 
      Japan.
FAU - Kisanuki, A
AU  - Kisanuki A
FAU - Toda, H
AU  - Toda H
FAU - Kuroiwa, R
AU  - Kuroiwa R
FAU - Murayama, T
AU  - Murayama T
FAU - Matsushita, R
AU  - Matsushita R
FAU - Toyonaga, K
AU  - Toyonaga K
FAU - Miyazono, Y
AU  - Miyazono Y
FAU - Nakao, S
AU  - Nakao S
FAU - Tanaka, H
AU  - Tanaka H
LA  - eng
PT  - Journal Article
PL  - England
TA  - Eur Heart J
JT  - European heart journal
JID - 8006263
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Flow Velocity/physiology
MH  - Bradycardia/physiopathology
MH  - Cardiac Catheterization
MH  - Cardiac Complexes, Premature/diagnostic imaging/*physiopathology
MH  - Diastole/physiology
MH  - Echocardiography, Doppler
MH  - Female
MH  - Hemodynamics/*physiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve/diagnostic imaging/physiopathology
MH  - Myocardial Contraction/physiology
MH  - Prospective Studies
MH  - Pulse/*physiology
MH  - Systole/physiology
MH  - Ventricular Function, Left/*physiology
EDAT- 1993/08/01 00:00
MHDA- 1993/08/01 00:01
CRDT- 1993/08/01 00:00
PHST- 1993/08/01 00:00 [pubmed]
PHST- 1993/08/01 00:01 [medline]
PHST- 1993/08/01 00:00 [entrez]
AID - 10.1093/eurheartj/14.8.1044 [doi]
PST - ppublish
SO  - Eur Heart J. 1993 Aug;14(8):1044-9. doi: 10.1093/eurheartj/14.8.1044.