PMID- 7692876
OWN - NLM
STAT- MEDLINE
DCOM- 19931214
LR  - 20180215
IS  - 1015-2008 (Print)
IS  - 1015-2008 (Linking)
VI  - 61
IP  - 3-4
DP  - 1993
TI  - Characterisation of human tumour cell lines using antibodies to intermediate 
      filaments.
PG  - 197-9
AB  - The human hepatoma cell line G2 (Hep G2) has been compared to lung carcinoma, 
      sarcoma and skin fibroblasts for the expression of intermediate filaments, i.e. 
      vimentin and cytokeratin. The immunofluorescence study revealed that, in 
      contradiction to Szecheng et al. (1987), cytokeratin and vimentin are absent in 
      Hep G2. Human skin fibroblasts and sarcoma cells expressed vimentin as expected 
      for their mesenchymal origin, but a positive reaction to vimentin could also be 
      shown in lung carcinoma cells. However, the vimentin filament structure of both 
      these tumour cell lines was different in comparison with skin fibroblasts. 
      Therefore determining the exact tissue origin of tumour cell lines by means of 
      intermediate filament characterization remains doubtful.
FAU - Moorthi, C
AU  - Moorthi C
AD  - Institute of Human Genetics, University of Hamburg, FRG.
FAU - Willers, I
AU  - Willers I
FAU - Ressler, B
AU  - Ressler B
FAU - Goedde, H W
AU  - Goedde HW
LA  - eng
PT  - Journal Article
PL  - Switzerland
TA  - Pathobiology
JT  - Pathobiology : journal of immunopathology, molecular and cellular biology
JID - 9007504
RN  - 0 (Biomarkers, Tumor)
RN  - 0 (Vimentin)
RN  - 68238-35-7 (Keratins)
SB  - IM
MH  - Biomarkers, Tumor/immunology
MH  - Fluorescent Antibody Technique
MH  - Humans
MH  - In Vitro Techniques
MH  - Intermediate Filaments/*immunology
MH  - Keratins/immunology
MH  - Tumor Cells, Cultured/immunology/*ultrastructure
MH  - Vimentin/immunology
EDAT- 1993/01/01 00:00
MHDA- 1993/01/01 00:01
CRDT- 1993/01/01 00:00
PHST- 1993/01/01 00:00 [pubmed]
PHST- 1993/01/01 00:01 [medline]
PHST- 1993/01/01 00:00 [entrez]
AID - 10.1159/000163793 [doi]
PST - ppublish
SO  - Pathobiology. 1993;61(3-4):197-9. doi: 10.1159/000163793.