PMID- 7694250
OWN - NLM
STAT- MEDLINE
DCOM- 19931216
LR  - 20190726
IS  - 0147-8389 (Print)
IS  - 0147-8389 (Linking)
VI  - 16
IP  - 10
DP  - 1993 Oct
TI  - Improvement of cardiac function in patients with severe congestive heart failure 
      and coronary artery disease by dual chamber pacing with shortened AV delay.
PG  - 2034-43
AB  - Medical therapy often fails to control symptoms of severe heart failure. The 
      possibility of modifying to some degree the global ventricular performance with 
      the implantation of a physiological dual chamber pacemaker, set with a short 
      atrioventricular delay (100 msec), has been adopted in two patients with severe 
      heart failure due to coronary artery disease. The baseline clinical condition of 
      both patients was characterized by leg edema, ascites, dyspnea at rest, or even 
      orthopnea with a functional New York Heart Association (NYHA) class III-IV. Acute 
      measurements of hemodynamic and echocardiographic parameters during stepwise 
      shortening of AV interval guided the pacemaker implantation and setting of AV 
      delay in the chronic phase. Within a few days after pacemaker implantation, both 
      patients considerably improved their clinical status as well as their functional 
      NYHA class, improving to class II in one patient and to class II-III in the other 
      patient. In addition, modification of systolic and diastolic parameters 
      paralleled these improvements functional class and clinical condition. Pacemaker 
      therapy in severe heart failure refractory to medical therapy can be of 
      considerable benefit in patients whose quality-of-life is severely compromised 
      when pharmacological therapy is no longer effective. Acute hemodynamic and 
      echocardiographic testing is useful in assessing the most appropriate AV delay 
      and pacing mode.
FAU - Auricchio, A
AU  - Auricchio A
AD  - Department of Cardiac Surgery, Universita di Roma Tor Vergata, European Hospital, 
      Italy.
FAU - Sommariva, L
AU  - Sommariva L
FAU - Salo, R W
AU  - Salo RW
FAU - Scafuri, A
AU  - Scafuri A
FAU - Chiariello, L
AU  - Chiariello L
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Pacing Clin Electrophysiol
JT  - Pacing and clinical electrophysiology : PACE
JID - 7803944
SB  - IM
CIN - Pacing Clin Electrophysiol. 1994 May;17(5 Pt 1):995-7. PMID: 7517539
MH  - Aged
MH  - Cardiac Pacing, Artificial/*methods
MH  - Coronary Disease/complications/physiopathology/*therapy
MH  - Echocardiography
MH  - Heart Failure/complications/physiopathology/*therapy
MH  - Hemodynamics/physiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Pacemaker, Artificial
EDAT- 1993/10/01 00:00
MHDA- 1993/10/01 00:01
CRDT- 1993/10/01 00:00
PHST- 1993/10/01 00:00 [pubmed]
PHST- 1993/10/01 00:01 [medline]
PHST- 1993/10/01 00:00 [entrez]
AID - 10.1111/j.1540-8159.1993.tb00997.x [doi]
PST - ppublish
SO  - Pacing Clin Electrophysiol. 1993 Oct;16(10):2034-43. doi: 
      10.1111/j.1540-8159.1993.tb00997.x.