PMID- 7699909
OWN - NLM
STAT- MEDLINE
DCOM- 19950501
LR  - 20110727
IS  - 0047-1852 (Print)
IS  - 0047-1852 (Linking)
VI  - 53
IP  - 3
DP  - 1995 Mar
TI  - [Renal failure].
PG  - 703-9
AB  - Renal failure is a common complication of multiple myeloma, because the kidney is 
      a major target organ for the deposition of paraproteins such as Bence Jones 
      protein (BJP), light chain fragment of monoclonal immunoglobulins, secreted by 
      plasmacytoma. There are three forms of renal involvements related to multiple 
      myeloma. The most common form is cast nephropathy ("myeloma kidney") due to 
      precipitation of BJP combined with Tamm-Horsfall protein in the distal nephron. 
      Other two forms are amyloid nephropathy and light chain deposition disease 
      (LCDD). Renal failure is usually arising from myeloma kidney and is exacerbated 
      by many other factors, for example, concurrently imposed chemical agents. In this 
      manuscript, the mechanism of renal failure mainly due to myeloma kidney and its 
      managements are mainly described.
FAU - Arai, T
AU  - Arai T
AD  - Third Department of Internal Medicine, Teikyo University School of Medicine.
FAU - Matsuzaki, K
AU  - Matsuzaki K
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Nihon Rinsho
JT  - Nihon rinsho. Japanese journal of clinical medicine
JID - 0420546
SB  - IM
MH  - Humans
MH  - Multiple Myeloma/*complications
MH  - Renal Insufficiency/*etiology/therapy
RF  - 20
EDAT- 1995/03/01 00:00
MHDA- 1995/03/01 00:01
CRDT- 1995/03/01 00:00
PHST- 1995/03/01 00:00 [pubmed]
PHST- 1995/03/01 00:01 [medline]
PHST- 1995/03/01 00:00 [entrez]
PST - ppublish
SO  - Nihon Rinsho. 1995 Mar;53(3):703-9.