PMID- 7704099
OWN - NLM
STAT- MEDLINE
DCOM- 19950511
LR  - 20190904
IS  - 0918-8959 (Print)
IS  - 0918-8959 (Linking)
VI  - 41
IP  - 6
DP  - 1994 Dec
TI  - Insulin sensitivity and glycemic control before and after parathyroidectomy in a 
      diabetic patient with familial multiple endocrine neoplasia type 1.
PG  - 731-5
AB  - We treated a diabetic patient with familial multiple endocrine neoplasia type 1 
      (MEN 1) who had undergone total pancreatoduodenectomy. The patient received 
      insulin and showed signs of symptomatic primary hyperparathyroidism (PHPT). The 
      insulin requirement to control blood glucose before and after parathyroidectomy 
      was compared by using an artificial pancreas. The insulin infusion rate during 
      the day and at night was reduced to about one-third and half, respectively, after 
      parathyroidectomy with autotransplantation of parathyroid tissues into the 
      forearm. The daily insulin dose was reduced from 36 units to 14 units 2 weeks 
      after surgery, and glycemic control showed further improvement 2 months after 
      surgery with the same dose of insulin for up to 6 months. These observations 
      suggest that insulin sensitivity increases after surgical correction of PHPT.
FAU - Furuto-Kato, S
AU  - Furuto-Kato S
AD  - Department of Internal Medicine, Kyoto University Faculty of Medicine, Japan.
FAU - Shimatsu, A
AU  - Shimatsu A
FAU - Kuzuya, H
AU  - Kuzuya H
FAU - Matsuda, K
AU  - Matsuda K
FAU - Nakao, K
AU  - Nakao K
FAU - Imura, H
AU  - Imura H
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - Endocr J
JT  - Endocrine journal
JID - 9313485
RN  - 0 (Blood Glucose)
RN  - 0 (Insulin)
SB  - IM
MH  - Adult
MH  - Blood Glucose/*metabolism
MH  - Diabetes Complications
MH  - Diabetes Mellitus/blood/*drug therapy
MH  - Female
MH  - Humans
MH  - Insulin/administration & dosage/*pharmacology/therapeutic use
MH  - Insulin Infusion Systems
MH  - Multiple Endocrine Neoplasia Type 1/blood/complications/*surgery
MH  - Pancreaticoduodenectomy
MH  - *Parathyroidectomy
EDAT- 1994/12/01 00:00
MHDA- 1994/12/01 00:01
CRDT- 1994/12/01 00:00
PHST- 1994/12/01 00:00 [pubmed]
PHST- 1994/12/01 00:01 [medline]
PHST- 1994/12/01 00:00 [entrez]
AID - 10.1507/endocrj.41.731 [doi]
PST - ppublish
SO  - Endocr J. 1994 Dec;41(6):731-5. doi: 10.1507/endocrj.41.731.