PMID- 7712735
OWN - NLM
STAT- MEDLINE
DCOM- 19950517
LR  - 20151119
IS  - 0277-3740 (Print)
IS  - 0277-3740 (Linking)
VI  - 14
IP  - 1
DP  - 1995 Jan
TI  - Current clinician's opinions on risk factors in corneal grafting. Results of a 
      survey among surgeons in the eurotransplant area.
PG  - 39-42
AB  - During 1992 a questionnaire was sent to 57 cornea transplant centers in the 
      Eurotransplant area, i.e., the Netherlands, Germany, Belgium, and Austria. 
      Questions included the number of grafts transplanted in each center in 1991, the 
      indications for cornea transplants, and surgeons' opinions on risk factors and 
      indications for human leukocyte antigen (HLA)-matched grafts. A response rate of 
      89% (51 of 57) was achieved. The total number of grafts in the 51 reporting 
      centers was 2,156 [average 42 (range: 3-303)]. In 19.3% of the cases HLA-matched 
      donor tissue was used (range: 0-64%). Matched transplants were performed in 
      high-risk cases. The term high-risk is not standardized by any means. Foremost, 
      HLA-matched donor corneas were requested for regraft after immunologic failure of 
      a previous transplant and in cases showing more than two quadrants of deep 
      stromal vascularization. This survey has shown important differences in 
      management of high-risk cases: variance in indications for HLA-matched grafting 
      and no consistency in the weighing of the importance of HLA-A, HLA-B, and HLA-DR 
      antigens nor consistency in the use of information on circulating antibodies. For 
      proper allocation of available donor tissue for corneal transplants in the 
      Eurotransplant area, a mutually accepted protocol defining indications for 
      matched grafting is needed.
FAU - Beekhuis, W H
AU  - Beekhuis WH
AD  - Cornea Service, The Eye Hospital, Rotterdam, The Netherlands.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cornea
JT  - Cornea
JID - 8216186
RN  - 0 (HLA Antigens)
SB  - IM
MH  - *Attitude of Health Personnel
MH  - Cornea/immunology
MH  - Corneal Diseases/*surgery
MH  - Corneal Transplantation/*adverse effects
MH  - Europe
MH  - Graft Survival/immunology
MH  - HLA Antigens/analysis
MH  - Histocompatibility Testing
MH  - Humans
MH  - Ophthalmology/*statistics & numerical data
MH  - Reoperation
MH  - Risk Factors
MH  - Surveys and Questionnaires
MH  - Tissue Donors
EDAT- 1995/01/01 00:00
MHDA- 1995/01/01 00:01
CRDT- 1995/01/01 00:00
PHST- 1995/01/01 00:00 [pubmed]
PHST- 1995/01/01 00:01 [medline]
PHST- 1995/01/01 00:00 [entrez]
PST - ppublish
SO  - Cornea. 1995 Jan;14(1):39-42.