PMID- 7715922 OWN - NLM STAT- MEDLINE DCOM- 19950515 LR - 20180217 IS - 0030-3755 (Print) IS - 0030-3755 (Linking) VI - 209 IP - 1 DP - 1995 TI - Effects on the corneal endothelium six months following photorefractive keratectomy. PG - 17-20 AB - Photorefractive keratectomy (PRK) with a 193-nm excimer laser has been shown not to destroy endothelial cells in vivo. However, this laser could damage endothelial cell metabolism, and result in damage over a longer term. In this paper, a comparison between the number and shape of corneal endothelial cells has been performed in 25 patients before and 6 months after PRK. These patients underwent treatment with myopic correction ranging from 2.5 to 17 dpt and with an estimated corneal thinning ranging from 25 to 170 microns. No significant changes in the number (p = 0.167) and shape (p = 0.075) of endothelial cells have been found. These results show that there are no long-term damages after PRK even in severely myopic eyes. FAU - Rosa, N AU - Rosa N AD - Eye Department, University Federico II, Naples, Italy. FAU - Cennamo, G AU - Cennamo G FAU - Del Prete, A AU - Del Prete A FAU - Pastena, B AU - Pastena B FAU - Sebastiani, A AU - Sebastiani A LA - eng PT - Journal Article PL - Switzerland TA - Ophthalmologica JT - Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde JID - 0054655 SB - IM MH - Adult MH - Cell Count MH - Cornea/*surgery MH - Endothelium, Corneal/*cytology MH - Female MH - Follow-Up Studies MH - Humans MH - *Laser Therapy MH - Male MH - Middle Aged MH - Myopia/*surgery MH - Prospective Studies EDAT- 1995/01/01 00:00 MHDA- 1995/01/01 00:01 CRDT- 1995/01/01 00:00 PHST- 1995/01/01 00:00 [pubmed] PHST- 1995/01/01 00:01 [medline] PHST- 1995/01/01 00:00 [entrez] AID - 10.1159/000310568 [doi] PST - ppublish SO - Ophthalmologica. 1995;209(1):17-20. doi: 10.1159/000310568.