PMID- 7742594
OWN - NLM
STAT- MEDLINE
DCOM- 19950612
LR  - 20091111
IS  - 0007-4551 (Print)
IS  - 0007-4551 (Linking)
VI  - 81
IP  - 12
DP  - 1994 Dec
TI  - Interphase cytogenetic studies of bladder cancer.
PG  - 1060-6
AB  - Transitional cell carcinomas of human urinary bladder were studied by interphase 
      fluorescence in situ hybridization (FISH). With current hybridization to isolated 
      nuclei, 26 tumors were investigated and nonrandom +7, -9 and -10 were identified. 
      Monosomy 11, tetraploidies and polyploidies were detected in invasive and 
      poor-differentiated tumors. Hybridization on frozen sections offers another means 
      of analysing surgical samples. FISH to vesical washings can be applied to monitor 
      tumor progression. Hybridizations on paraffine sections and on tissues previously 
      stored in liquid nitrogen allow retrospective studies of the archived materials. 
      Our data suggest that the interphase FISH can become a powerful tool for 
      cytogenetic studies of bladder cancer.
FAU - Wang, M R
AU  - Wang MR
AD  - Laboratoire d'histologie-embryologie-cytogenetique, faculte de medecine, 
      Clermont-Ferrand, France.
FAU - Perissel, B
AU  - Perissel B
FAU - Taillandier, J
AU  - Taillandier J
FAU - Malet, P
AU  - Malet P
LA  - eng
PT  - Journal Article
PL  - France
TA  - Bull Cancer
JT  - Bulletin du cancer
JID - 0072416
SB  - IM
MH  - Carcinoma, Transitional Cell/*genetics/pathology
MH  - Chromosome Aberrations
MH  - Humans
MH  - *In Situ Hybridization, Fluorescence
MH  - Interphase
MH  - Tissue Preservation
MH  - Urinary Bladder Neoplasms/*genetics/pathology
EDAT- 1994/12/01 00:00
MHDA- 1994/12/01 00:01
CRDT- 1994/12/01 00:00
PHST- 1994/12/01 00:00 [pubmed]
PHST- 1994/12/01 00:01 [medline]
PHST- 1994/12/01 00:00 [entrez]
PST - ppublish
SO  - Bull Cancer. 1994 Dec;81(12):1060-6.