PMID- 7749125
OWN - NLM
STAT- MEDLINE
DCOM- 19950620
LR  - 20071115
IS  - 0340-4684 (Print)
IS  - 0340-4684 (Linking)
VI  - 20
IP  - 2-3
DP  - 1994
TI  - European organization for cord blood banking.
PG  - 601-8
AB  - Cord blood transplant has been performed in children with malignant and 
      nonmalignant hematological disorders. Most often, the donor was an HLA-identical 
      or a partially mismatched sibling. The results seem to demonstrate that one cord 
      blood contains enough hematopoietic stem cells to reconstitute the marrow in a 
      child, the incidence of graft vs. host disease (GVHD) has been very low in 
      matched transplants, and the immune reconstitution has not been different from a 
      bone marrow transplant. In Paris, seven children have received an HLA-identical 
      sibling cord transplant; five are alive and well, and two had no engraftment. 
      Several questions remain: results in adults, use of cord blood for mis-matched or 
      matched unrelated transplants, standardization of methods of collection, 
      cryopreservation, and banking. A European cord blood banking group has been 
      created to coordinate this research.
FAU - Gluckman, E
AU  - Gluckman E
AD  - Bone Marrow Transplant Unit-Hopital Saint-Louis AP HP, University, Paris, France.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Blood Cells
JT  - Blood cells
JID - 7513567
SB  - IM
CIN - Blood Cells. 1994;20(2-3):627-9. PMID: 7749127
MH  - Adult
MH  - Anemia, Aplastic/therapy
MH  - Blood Banks/*organization & administration
MH  - Blood Cell Count
MH  - Blood Donors
MH  - Blood Preservation
MH  - Child
MH  - Child, Preschool
MH  - Chimera
MH  - Cryopreservation
MH  - Ethics, Medical
MH  - Europe
MH  - Fanconi Anemia/therapy
MH  - *Fetal Blood/cytology
MH  - Graft Survival
MH  - *Hematopoietic Stem Cell Transplantation
MH  - Histocompatibility Testing
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Precursor Cell Lymphoblastic Leukemia-Lymphoma/therapy
MH  - Registries
MH  - Retrospective Studies
MH  - Treatment Outcome
EDAT- 1994/01/01 00:00
MHDA- 1994/01/01 00:01
CRDT- 1994/01/01 00:00
PHST- 1994/01/01 00:00 [pubmed]
PHST- 1994/01/01 00:01 [medline]
PHST- 1994/01/01 00:00 [entrez]
PST - ppublish
SO  - Blood Cells. 1994;20(2-3):601-8.