PMID- 7749565
OWN - NLM
STAT- MEDLINE
DCOM- 19950620
LR  - 20191031
IS  - 0967-3849 (Print)
IS  - 0967-3849 (Linking)
VI  - 3
IP  - 2
DP  - 1995 Mar
TI  - Establishment of the marker order 
      pter-NRAS-NGFB-D1S189-D1S252-D1S440-D1S453-D1S514-CEN-D1S442-D1S498-qte r in 
      relation to the centromere on human chromosome 1.
PG  - 137-8
AB  - Recent developments in genetic linkage mapping of the human genome have generated 
      a large number of short tandem repeat polymorphic markers (Weissenbach et al. 
      1992, Gyapay et al. 1994), and eventual integration of these markers into a 
      physical map is a logical progression. A number of Genethon microsatellite (CA 
      repeat) markers have been provisionally localized to 1p13, but their exact 
      position with respect to other sequences is unknown. In order to confirm the 
      order of these markers and their position with respect to known genes within 1p13 
      and the centromere, we have isolated yeast artificial chromosomes (YACs) 
      corresponding to the markers and have carried out double and triple fluorescence 
      in situ hybridization (FISH) studies. Knowledge of both the order of 
      microsatellite markers and their integration with a physical map of known genes 
      can be an essential component in analysis of disease loci such as human cancer, 
      where regions of chromosomes showing high levels of loss of heterozygosity need 
      to be mapped in detail.
FAU - Hoggard, N
AU  - Hoggard N
AD  - CRC Department of Cancer Genetics, Paterson Institute for Cancer Research, 
      Christie Hospital, Manchester, UK.
FAU - Brintnell, B
AU  - Brintnell B
FAU - Hey, Y
AU  - Hey Y
FAU - Jones, D
AU  - Jones D
FAU - Weissenbach, J
AU  - Weissenbach J
FAU - Mitchell, E
AU  - Mitchell E
FAU - Varley, J
AU  - Varley J
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Chromosome Res
JT  - Chromosome research : an international journal on the molecular, supramolecular 
      and evolutionary aspects of chromosome biology
JID - 9313452
RN  - 0 (DNA, Satellite)
RN  - 0 (Genetic Markers)
SB  - IM
MH  - Centromere/*genetics
MH  - *Chromosome Mapping
MH  - Chromosomes, Artificial, Yeast
MH  - Chromosomes, Human, Pair 1/*genetics
MH  - DNA, Satellite/*genetics
MH  - Genetic Linkage
MH  - Genetic Markers/*genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Male
EDAT- 1995/03/01 00:00
MHDA- 1995/03/01 00:01
CRDT- 1995/03/01 00:00
PHST- 1995/03/01 00:00 [pubmed]
PHST- 1995/03/01 00:01 [medline]
PHST- 1995/03/01 00:00 [entrez]
AID - 10.1007/BF00710677 [doi]
PST - ppublish
SO  - Chromosome Res. 1995 Mar;3(2):137-8. doi: 10.1007/BF00710677.