PMID- 7757479
OWN - NLM
STAT- MEDLINE
DCOM- 19950628
LR  - 20190614
IS  - 0006-8993 (Print)
IS  - 0006-8993 (Linking)
VI  - 673
IP  - 1
DP  - 1995 Feb 27
TI  - Pattern of Fos and Jun expression in the female rat forebrain after sexual 
      behavior.
PG  - 53-60
AB  - Previous studies indicated that sexual behavior in female rats primed with 
      estradiol and progesterone induced expression of the immediate early gene (IEG) 
      c-Fos in various brain areas rich in estradiol receptors, including the medial 
      preoptic area (MPA), the medial amygdala (AMe), and the ventromedial nucleus of 
      the hypothalamus (VMN), and to a lesser extent areas with low densities of 
      estradiol receptors, such as the caudate nucleus, the dentate gyrus and the 
      cingulate cortex. The goal of the present experiment was to compare this pattern 
      of expression with the distribution of other IEG products within the Jun family. 
      The results indicate that in non-mated animals, Jun-B, c-Jun and Jun-D were 
      differentially present in several forebrain areas. As previously reported for 
      c-Fos, there was little effect of estradiol and progesterone treatment on the 
      brain expression of these Jun proteins. The most striking result was that sexual 
      behavior stimulated expression of Jun-B and c-Jun, but not Jun-D, in areas 
      containing high densities of estradiol receptors. Specifically, after sexual 
      behavior the MPA and the bed nucleus of the stria terminalis co-expressed c-Fos, 
      Jun-B, c-Jun. c-Fos was co-induced with Jun-B in the VMN, and with c-Jun in the 
      AMe. In contrast, there was no detectable increase in Jun-B, c-Jun or Jun-D in 
      either the caudate nucleus, dentate gyrus or cingulate cortex after sexual 
      behavior, although these regions expressed weak to moderate levels of either 
      Jun-B, c-Jun, or Jun-D basally.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Flanagan-Cato, L M
AU  - Flanagan-Cato LM
AD  - Laboratory of Neuroendocrinology, Rockefeller University, New York, NY 10021, 
      USA.
FAU - McEwen, B S
AU  - McEwen BS
LA  - eng
GR  - NS07080/NS/NINDS NIH HHS/United States
GR  - NS09026/NS/NINDS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Brain Res
JT  - Brain research
JID - 0045503
RN  - 0 (Proto-Oncogene Proteins c-fos)
RN  - 0 (Proto-Oncogene Proteins c-jun)
SB  - IM
MH  - Animals
MH  - Female
MH  - Gene Expression
MH  - Immunohistochemistry
MH  - Prosencephalon/*physiology
MH  - Proto-Oncogene Proteins c-fos/*genetics
MH  - Proto-Oncogene Proteins c-jun/*genetics
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Sexual Behavior, Animal/*physiology
EDAT- 1995/02/27 00:00
MHDA- 1995/02/27 00:01
CRDT- 1995/02/27 00:00
PHST- 1995/02/27 00:00 [pubmed]
PHST- 1995/02/27 00:01 [medline]
PHST- 1995/02/27 00:00 [entrez]
AID - 0006-8993(94)01395-X [pii]
AID - 10.1016/0006-8993(94)01395-x [doi]
PST - ppublish
SO  - Brain Res. 1995 Feb 27;673(1):53-60. doi: 10.1016/0006-8993(94)01395-x.