PMID- 7760511
OWN - NLM
STAT- MEDLINE
DCOM- 19950626
LR  - 20190825
IS  - 0021-4868 (Print)
IS  - 0021-4868 (Linking)
VI  - 36
IP  - 1
DP  - 1995 Jan
TI  - The use of the handgrip maneuver to identify left ventricular diastolic function 
      abnormalities by Doppler echocardiography in patients with coronary artery 
      disease.
PG  - 23-8
AB  - Doppler echocardiography accurately identifies diastolic dysfunction through the 
      assessment of transmitral flow patterns during the application of the handgrip 
      (HG) maneuver. In this study, 45 normal control patients (mean age 46 +/- 9, 
      group A) and 13 patients with coronary artery disease (CAD) (mean age 51 +/- 6, 
      group B) were involved. The effects of handgrip maneuver on transmitral flow 
      patterns were studied by Doppler echocardiography. Group B patients had higher 
      peak late diastolic filling velocities (A), lower peak early (E) to late 
      diastolic filling velocity ratios (E/A) and longer isovolumic relaxation times 
      (IVRT) compared to group A. On the other hand, systolic blood pressure (SBP), 
      heart rate (HR) and peak E velocity (E) did not change significantly (p > 0.05) 
      in either group, at rest. During the supine handgrip maneuver, NR (mean +/- 
      standard error of mean, +21 +/- 13%, p < 0.05) and SBP (+21 +/- 9%, p < 0.05) 
      increased significantly in both group A and group B (+21 +/- 13%, p < 0.05, +22 
      +/- 15%, p < 0.05, respectively). In group B, E/A ratio (-28 +/- 7%) decreased 
      significantly (p < 0.05) compared to group A (-20 +/- 6%), as a consequence of 
      significantly increased peak A velocity in group B (+7 +/- 5%) compared to group 
      A (+6 +/- 3%, p < 0.05). Deceleration time decreased significantly in both groups 
      (-10 +/- 6% vs -9 +/- 6%, p < 0.05). Isovolumic relaxation time (IVRT) 
      significantly increased in both groups (+18 +/- 7% vs +16 +/- 6%, p < 
      0.001).(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Tavli, T
AU  - Tavli T
AD  - Department of Cardiology, Medical School of Selcuk University, Konya, Turkey.
FAU - Cin, V G
AU  - Cin VG
FAU - Tavli, V
AU  - Tavli V
FAU - Wong, M
AU  - Wong M
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PL  - Japan
TA  - Jpn Heart J
JT  - Japanese heart journal
JID - 0401175
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Flow Velocity
MH  - Coronary Disease/*diagnostic imaging/*physiopathology
MH  - *Diastole
MH  - *Echocardiography, Doppler
MH  - Exercise Test
MH  - Female
MH  - *Hand Strength
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Reproducibility of Results
MH  - *Ventricular Function, Left
EDAT- 1995/01/01 00:00
MHDA- 1995/01/01 00:01
CRDT- 1995/01/01 00:00
PHST- 1995/01/01 00:00 [pubmed]
PHST- 1995/01/01 00:01 [medline]
PHST- 1995/01/01 00:00 [entrez]
AID - 10.1536/ihj.36.23 [doi]
PST - ppublish
SO  - Jpn Heart J. 1995 Jan;36(1):23-8. doi: 10.1536/ihj.36.23.