PMID- 7773951
OWN - NLM
STAT- MEDLINE
DCOM- 19950713
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 81
IP  - 1
DP  - 1995 May
TI  - Characterization and chromosomal assignment of yeast artificial chromosomes 
      containing human 3p13-p21-specific sequence tagged sites.
PG  - 1-12
AB  - Human chromosomal region 3p12-p23 is proposed to harbor at least three tumor 
      suppressor genes involved in the development of lung cancer, renal cell 
      carcinoma, and other neoplasias. In order to identify one of these genes we 
      defined sequence tagged sites (STSs) specific for 3p13-p24.2 by analyzing a 
      chromosome 3p14 microdissection library. STSs were used for isolating yeast 
      artificial chromosome (YAC) clones from the Centre d'Etude du Polymorphisme 
      Humain (CEPH) YAC libraries. Thirty-eight YACs were assembled into a contig 
      approximately 2.5 Mb in size spanning the t(3;8) and t(3;6) translocation 
      breakpoints associated with hereditary renal cell carcinoma and hematologic 
      malignancies, respectively. Chromosomal localization and chimeric status of 126 
      YACs was analyzed by fluorescence in situ hybridization (FISH). The order of 17 
      YACs determined by double-color FISH was in agreement with the STS-based 
      arrangement of the YAC-contig.
FAU - Michaelis, S C
AU  - Michaelis SC
AD  - Department of Medical Oncology (Cancer Research), University of Essen Medical 
      School, West German Cancer Center.
FAU - Bardenheuer, W
AU  - Bardenheuer W
FAU - Lux, A
AU  - Lux A
FAU - Schramm, A
AU  - Schramm A
FAU - Gockel, A
AU  - Gockel A
FAU - Siebert, R
AU  - Siebert R
FAU - Willers, C
AU  - Willers C
FAU - Schmidtke, K
AU  - Schmidtke K
FAU - Todt, B
AU  - Todt B
FAU - van der Hout, A H
AU  - van der Hout AH
AU  - et al.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
SB  - IM
MH  - Base Sequence
MH  - Chromosome Mapping
MH  - Chromosomes, Artificial, Yeast/*genetics
MH  - *Chromosomes, Human, Pair 3
MH  - Electrophoresis, Gel, Pulsed-Field
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Molecular Sequence Data
MH  - *Sequence Tagged Sites
MH  - Translocation, Genetic
EDAT- 1995/05/01 00:00
MHDA- 1995/05/01 00:01
CRDT- 1995/05/01 00:00
PHST- 1995/05/01 00:00 [pubmed]
PHST- 1995/05/01 00:01 [medline]
PHST- 1995/05/01 00:00 [entrez]
AID - 0165460894002088 [pii]
AID - 10.1016/0165-4608(94)00208-8 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1995 May;81(1):1-12. doi: 10.1016/0165-4608(94)00208-8.