PMID- 7774908
OWN - NLM
STAT- MEDLINE
DCOM- 19950707
LR  - 20190904
IS  - 0888-7543 (Print)
IS  - 0888-7543 (Linking)
VI  - 25
IP  - 1
DP  - 1995 Jan 1
TI  - High-resolution cytogenetic mapping of the short arm of chromosome 1 with newly 
      isolated 411 cosmid markers by fluorescence in situ hybridization: the precise 
      order of 18 markers on 1p36.1 on prophase chromosomes and "stretched" DNAs.
PG  - 114-23
AB  - A high-resolution cytogenetic map of the short arm of chromosome 1 with newly 
      isolated 411 cosmid markers was constructed by fluorescence in situ hybridization 
      (FISH). These markers were scattered throughout chromosome 1p, but they were 
      preferentially concentrated on R-band dominant regions such as 1p36, 1p34, 1p32, 
      1p22, and 1p13. Among these markers, 197 were localized on chromosome band 1p36, 
      a region frequently deleted in neuroblastoma. Of these, 18 were precisely ordered 
      on 1p36.1 by multicolor FISH of prophase chromosomes and "stretched" DNAs as 
      follows: 1pter-163-41-11-1-226-586-568-614-631-665-451-199-190-561-241-74-1 
      76-652-1cen. The high-density map of chromosome 1p constructed here can provide 
      useful landmarks for constructing a contig map of the short arm of chromosome 1 
      with YACs and cosmid clones and will expedite the identification of breakpoints 
      and/or tumor suppressor gene(s) associated with several types of malignant tumors 
      that frequently exhibit chromosomal aberrations or deletions of chromosome 1p.
FAU - Ariyama, T
AU  - Ariyama T
AD  - Department of Hygiene, Kyoto Prefectural University of Medicine, Japan.
FAU - Inazawa, J
AU  - Inazawa J
FAU - Ezaki, T
AU  - Ezaki T
FAU - Nakamura, Y
AU  - Nakamura Y
FAU - Horii, A
AU  - Horii A
FAU - Abe, T
AU  - Abe T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Genomics
JT  - Genomics
JID - 8800135
RN  - 0 (Genetic Markers)
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Animals
MH  - Cell Line
MH  - Chromosome Aberrations
MH  - Chromosome Banding
MH  - Chromosome Mapping
MH  - *Chromosomes, Human, Pair 1
MH  - *Cosmids
MH  - Cytogenetics
MH  - DNA/analysis/genetics
MH  - Genes, Tumor Suppressor
MH  - Genetic Markers
MH  - Humans
MH  - Hybrid Cells
MH  - In Situ Hybridization, Fluorescence
MH  - Metaphase
MH  - Mice
MH  - Neoplasms/genetics
EDAT- 1995/01/01 00:00
MHDA- 1995/01/01 00:01
CRDT- 1995/01/01 00:00
PHST- 1995/01/01 00:00 [pubmed]
PHST- 1995/01/01 00:01 [medline]
PHST- 1995/01/01 00:00 [entrez]
AID - 0888-7543(95)80116-4 [pii]
AID - 10.1016/0888-7543(95)80116-4 [doi]
PST - ppublish
SO  - Genomics. 1995 Jan 1;25(1):114-23. doi: 10.1016/0888-7543(95)80116-4.